Protein Alignment sqd and tardbpb

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_958884.1
• Gene: tardbpb / 325052
• ZFINID: ZDB-GENE-030131-3777
• Length: 412
• Species: Danio rerio
• Alignment Length: 329
• Identity: 92/329 - (27%)
• Similarity: 141/329 - (42%)
• Gaps: 86/329 - (26%)

  Fly     3 ENKQVDTEINGEDFTKDVTADGPGS--------------------------ENGDAGAAGSTN-- 39
            |..::.:|.:|......|:|..||:                          |||........|
Zfish    15 EPMEIPSEDDGTVLLSTVSAQFPGACGLRFRSPVSQCMRGVRLVDGILHAPENGWGNLVYVVNYP 79

  Fly    40 ------------GSSDNQSAASGQRDDDR--KLFVGGLSWETTEKELRDHFGKYGEIESINVKTD 90
                        ...|..||...:|.|.:  .|.|.||.|:|:|::|:|:||.:||:..:.||.|
Zfish    80 KETVLPDNKRKMDEIDASSATKIKRGDQKTSDLIVLGLPWKTSEQDLKDYFGTFGEVIMVQVKRD 144

  Fly    91 PQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHG--------KIFVGGLTTEI 147
            .:||.|:||.|:.|.:.|...|| ....|:|:.:..|.|...::.|        |:|||..|.::
Zfish   145 VKTGNSKGFGFVRFGDWETQSKV-MTQRHMIDGRWCDCKLPNSKQGIDEPMRSRKVFVGRCTEDM 208

  Fly   148 SDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVT-----DLLKTPKQKIAGKEVD 207
            :.:|::.:|.|:|.:.:|.:|     ...:.|.|:||..:||..     ||:      |.|..|.
Zfish   209 TADELRQFFMQYGEVTDVFIP-----KPFRAFAFVTFADDQVAAALCGEDLI------IKGVSVH 262

  Fly   208 VKRATPKPEN--QMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGA--GG 268
            :..|.||..|  |||      .|.|..|  .|:||:|       ..||....|||.||..:  |.
Zfish   263 ISNAEPKHNNTRQMM------ERAGRFG--NGFGGQG-------FAGSRSNMGGGGGGSSSSLGN 312

  Fly   269 YGDY 272
            :|::
Zfish   313 FGNF 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	29/70 (41%)
		RRM2_hnRNPD_like	137..211	CDD:240775	22/78 (28%)
tardbpb	NP_958884.1	TDP43_N	5..78	CDD:465833	10/62 (16%)
		RRM1_TDP43	111..184	CDD:409760	30/73 (41%)
		RRM2_TDP43	197..267	CDD:409761	22/80 (28%)