Protein Alignment sqd and HNRNPAB

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_112556.2
• Gene: HNRNPAB / 3182
• HGNCID: 5034
• Length: 332
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 130/341 - (38%)
• Similarity: 179/341 - (52%)
• Gaps: 61/341 - (17%)

  Fly    24 GPGSENGDAGA-----AGSTNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIE 83
            |.|:..|..||     :|:.||:..:|..||...:|..|:|||||||:|::|:|:|:|.|:||:.
Human    33 GTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVV 97

  Fly    84 SINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARH----GKIFVGGLT 144
            ...:|.||.|||||||.||:|.:..:::||....||.::.:.:|||||.|..    .|||||||.
Human    98 DCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLN 162

  Fly   145 TEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVK 209
            .|.::|:|:.|||:||.|..:|:|.|.:.::|:||.||||..|:.|..:|:.....::|.:.::|
Human   163 PEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIK 227

  Fly   210 RATPK---PENQMMGGMRGGPRGGMRGGRGGYGGRG-------GYNNQWD-GQGSYGGYGGGYGG 263
            .|.||   .:.|...|.||....|.||..||.||.|       ||.|.|: |.|...|||.||||
Human   228 VAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGG 292

  Fly   264 YGAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNG 328
            |....|| ||  ||..||||..                                      |..|.
Human   293 YDYSPYG-YY--GYGPGYDYSQ--------------------------------------GSTNY 316

  Fly   329 GKQRGGGGRQQRHQPY 344
            ||.:..||.|..::||
Human   317 GKSQRRGGHQNNYKPY 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	33/70 (47%)
		RRM2_hnRNPD_like	137..211	CDD:240775	31/73 (42%)
HNRNPAB	NP_112556.2	CBFNT	1..70	CDD:311868	12/36 (33%)
		RRM1_hnRNPAB	66..145	CDD:410151	37/78 (47%)
		RRM2_hnRNPAB	150..229	CDD:409997	31/78 (40%)