Protein Alignment sqd and RBM34

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_055829.2
• Gene: RBM34 / 23029
• HGNCID: 28965
• Length: 430
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 60/254 - (23%)
• Similarity: 103/254 - (40%)
• Gaps: 44/254 - (17%)

  Fly     2 AENKQVDTE--INGEDFTKDV-TADGPGSENGDAGA-AGSTNGSSDNQSAASGQR---------- 52
            ||.|..|.|  :...|..::: ...|...:|...|. ........|.:.....||
Human   115 AEKKLADRESALASADLEEEIHQKQGQKRKNSQPGVKVADRKILDDTEDTVVSQRKKIQINQEEE 179

  Fly    53 --DDDRKLFVGGLSWETTEKELRDHFGKYGEIESIN-----------------VKTDPQTGRSRG 98
              .::|.:|||.|.....:|:|:..|.:||:|||:.                 :|......:...
Human   180 RLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNI 244

  Fly    99 FAFIVFTN----TEAIDKVSA--ADEHIINSKKVDPKKAKARHGK--IFVGGLTTEISDEEIKTY 155
            .|::||..    |:|:.:..|  ||...|   :||.....:...|  :|||.|..::.:..|:.:
Human   245 NAYVVFKEESAATQALKRNGAQIADGFRI---RVDLASETSSRDKRSVFVGNLPYKVEESAIEKH 306

  Fly   156 FGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPK 214
            |...|:|:.|.:..||.....|||.::.|::...|...||....::.|:::.|.|:..|
Human   307 FLDCGSIMAVRIVRDKMTGIGKGFGYVLFENTDSVHLALKLNNSELMGRKLRVMRSVNK 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	24/93 (26%)
		RRM2_hnRNPD_like	137..211	CDD:240775	21/75 (28%)
RBM34	NP_055829.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..123		4/7 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..153		3/18 (17%)
		RRM1_RBM34	185..276	CDD:409828	23/93 (25%)
		RRM2_RBM34	288..360	CDD:409829	19/71 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	365..395		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	411..430