DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Droj2 and dnaja1

DIOPT Version :9

Sequence 1:	NP_650283.1	Gene:	Droj2 / 41646	FlyBaseID:	FBgn0038145	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_955956.1	Gene:	dnaja1 / 323922	ZFINID:	ZDB-GENE-030131-2642	Length:	398	Species:	Danio rerio

Alignment Length:	414	Identity:	233/414 - (56%)
Similarity:	294/414 - (71%)	Gaps:	27/414 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYD 65
            ||||||:||:|||||:|:|:|||||||||||||||||||.||||||.|||||||||||.||:|||
Zfish     1 MVKETGFYDMLGVKPSASPEELKKAYRKLALKYHPDKNPTEGEKFKQISQAYEVLSDAKKREVYD 65

  Fly    66 EGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGGR-RRERRGKDVVHQMSVQLEELYNGAT 129
            .|||.|||:||  :|...:|||.|:.|||      |||| .||||||:||||::|.||:||||.|
Zfish    66 RGGEKAIKEGG--NGGSCSPMDIFDLFFG------GGGRMHRERRGKNVVHQLTVSLEDLYNGTT 122

  Fly   130 RKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQ 194
            |||.|||||||||||||||:||.||.|..|||.||:.|:..:|||::|.|..||..|.|.|:.:.
Zfish   123 RKLALQKNVICDKCEGRGGRKGVIEVCPLCRGVGVQVRLHHLAPGMVQQISTVCEGCQGQGQRLG 187

  Fly   195 EKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAH 259
            .:||||.|:|||.:|::|:|||||:|||:|||||||.||||.||..:||||||:||::.|..:..
Zfish   188 HRDRCKTCTGRKILRQKKILEVHIDKGMKDGQKIVFHGEGDQEPGLKPGDIIIVLDQRAHPLYTR 252

  Fly   260 AGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKG 324
            .|.||::.|.|||||:|||||:.:||||.|.|::::.|||:|:....||:..||||:.:.|.|||
Zfish   253 QGDDLIVSMELQLVESLCGFQKPIKTLDSRTLLITSHPGELIKPGDKKCVMNEGMPMHRRPFEKG 317

  Fly   325 TLIIQFEVIFPE--VINPSVVPTLKQCLPPAPE--------VDIPIDAEQTVLEDFDPKQRRQQH 379
            .|||...|:|||  .:..:.:..|::.||...|        .|:.|.|:   |||.|....|..:
Zfish   318 KLIIHSNVVFPEENFLPLNKLKELERFLPNKQENMESDSMDDDLYIYAD---LEDCDLSHERHHY 379

  Fly   380 QRMAYDEDDGGYQDGPRVQQCTSS 403
            .   |.|::..|..|.  .||.:|
Zfish   380 H---YIEEEDFYPSGG--VQCQTS 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	229/406 (56%)
		DnaJ	7..65	CDD:278647	48/57 (84%)
		DnaJ_C	112..336	CDD:199909	130/223 (58%)
		DnaJ_zf	140..206	CDD:199908	36/65 (55%)
dnaja1	NP_955956.1	PTZ00037	2..395	CDD:240236	229/408 (56%)
		DnaJ	7..65	CDD:278647	48/57 (84%)
		DnaJ_C	104..330	CDD:199909	132/225 (59%)
		DnaJ_zf	133..199	CDD:199908	36/65 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1502
eggNOG	1	0.900	-	-		E2759_KOG0712
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	450	1.000	Inparanoid score	I1590
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	1	1.000	-	-		FOG0000718
OrthoInspector	1	1.000	-	-		oto40055
orthoMCL	1	0.900	-	-		OOG6_100614
Panther	1	1.100	-	-	LDO	PTHR43888
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R684
SonicParanoid	1	1.000	-	-		X359
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870