Protein Alignment PK2-R1 and ghsra

DIOPT Version :10

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001139744.1
• Gene: ghsra / 795753
• ZFINID: ZDB-GENE-070912-238
• Length: 360
• Species: Danio rerio
• Alignment Length: 345
• Identity: 117/345 - (33%)
• Similarity: 172/345 - (49%)
• Gaps: 49/345 - (14%)

  Fly    90 NASTMAADSPVD-ESLTLRTALTVCYALIFVAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSD 153
            ||:....:.||: ..:.:.|.:||...|.|..||.|||:|.:|:::...|.|.||.||.::|.||
Zfish    19 NATYWGIEQPVNIFPIPVLTGVTVTCVLFFFVGVTGNLMTILVVTKYKDMRTTTNLYLSSMAFSD 83

  Fly   154 LILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHT 218
            |::.:. :|.:||.:|....:.|.:.:|.:...:||....:|:|.|||.:||||.|||.|.|...
Zfish    84 LLIFLC-MPLDLYRIWRYRPWNFGNILCKLFQFVSECCTYSTILNITALSVERYFAICFPLRAKV 147

  Fly   219 MSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGYSCTMENDFYAHVFAV-SGF-------- 274
            :....|....|..:|:.:|..|.|..:...|.::| |.:....|:..|..:|: ||.
Zfish   148 VVTKGRVRGVILVLWIVSFFSAGPVFVLVGVEHEN-GTNSWDTNECKATEYAIRSGLLTIMVWVS 211

  Fly   275 -IFFGGPMTAICVLYVLIGVKL-KRSRLLQSLPRRTFDANRGLNAQGR------VIRMLVAVAVA 331
             |||..|:..:.|||.|||.|| ||.|           ...|.||..|      .::||..|..|
Zfish   212 SIFFFLPVFCLTVLYSLIGRKLWKRKR-----------ETIGENASSRDKSNRQTVKMLAVVVFA 265

  Fly   332 FFLCWAPFHAQRLM----AVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMS 392
            |.|||.|||..|.:    ...|..:::|      .:.|..::.:   ||::||..|||:||||||
Zfish   266 FVLCWLPFHVGRYLISKSTEMGSPVMSI------ISHYCNLISF---VLFYLSAAINPILYNIMS 321

  Fly   393 HKFREAFKITLTRQFGLARN 412
            .|:|.|    ..:.||| ||
Zfish   322 KKYRMA----ACKLFGL-RN 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tmA_capaR	108..399	CDD:320262	107/311 (34%)
		TM helix 1	108..135	CDD:320262	12/26 (46%)
		TM helix 2	142..168	CDD:320262	11/25 (44%)
		TM helix 3	181..211	CDD:320262	13/29 (45%)
		TM helix 4	223..245	CDD:320262	6/21 (29%)
		TM helix 5	265..294	CDD:320262	14/38 (37%)
		TM helix 6	316..346	CDD:320262	15/39 (38%)
		TM helix 7	367..392	CDD:320262	11/24 (46%)
ghsra	NP_001139744.1	7tm_GPCRs	38..328	CDD:475119	108/315 (34%)
		TM helix 1	40..64	CDD:410628	11/23 (48%)
		TM helix 2	73..94	CDD:410628	8/21 (38%)
		TM helix 3	111..133	CDD:410628	7/21 (33%)
		TM helix 4	156..172	CDD:410628	4/15 (27%)
		TM helix 5	204..227	CDD:410628	6/22 (27%)
		TM helix 6	256..278	CDD:410628	11/21 (52%)
		TM helix 7	296..321	CDD:410628	12/27 (44%)