Protein Alignment PK2-R1 and Nmur1

DIOPT Version :10

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_017452122.1
• Gene: Nmur1 / 65276
• RGDID: 619867
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 147/434 - (33%)
• Similarity: 212/434 - (48%)
• Gaps: 79/434 - (18%)

  Fly    49 NPSESPEMLLLKNDKFLTHV-AHLLNITTENLS-NLLGSTNGTNASTMAADSPVDESLTLRTALT 111
            :|:.|..:|...:.:|..|. ...||:|.|:|. ..||...                  ::..|.
  Rat     5 SPNASTGLLSCNDSEFKEHFDLEDLNLTHEDLRLKYLGPQQ------------------VKQFLP 51

  Fly   112 VC--YALIFVAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMY 174
            :|  |.||||.|.|||.:||.||.|...|||.||||||:||||||::|:.|:|.|||.:.:  .|
  Rat    52 ICVTYLLIFVVGTLGNGLTCTVILRQKAMHTPTNFYLFSLAVSDLLVLLVGLPLELYEMQH--NY 114

  Fly   175 PFT--DAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAF 237
            ||.  ...|....:|.|....|:||.:||.:||||:|:.||.:..::...:...:.:.|||:.|.
  Rat   115 PFQLGAGGCYFRILLLETVCLASVLNVTALSVERYVAVVHPLQAKSVMTRTHVRRMLGAIWVFAI 179

  Fly   238 LLALPQAM--QFSVVY------QNEGYSCTMEND--FYAHVFAVSGFIFFGGPMTAICVLYVLIG 292
            |.:||...  ..|.:|      ..:..:||:...  ||..|...:..:||..||..|.|||:|||
  Rat   180 LFSLPNTSLHGLSPLYVPCRGPVPDSVTCTLVRPQFFYKLVIQTTILLFFCLPMVTISVLYLLIG 244

  Fly   293 VKLKRSR-LLQSLPRRTFDA------NRGLNAQGR----VIRMLVAVAVAFFLCWAPFHAQRLM- 345
            ::|:|.| |||...:....|      :|.:..:.|    |.:||:|:.:.|..||.||||.|||
  Rat   245 LRLRRERILLQEEVKGRISAAARQASHRSIQLRDRERRQVTKMLIALVIVFGTCWVPFHADRLMW 309

  Fly   346 -----AVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLTR 405
                 ...||.|.            |:.:...|||..:|.:..||:|||:||.:|||:|:.||
  Rat   310 SMVSHWTDGLRLA------------FQSVHLASGVFLYLGSAANPVLYNLMSTRFRESFRETL-- 360

  Fly   406 QFGL-ARNHHHQQSQHHQHNYSALLRQNGSMRLQPASCSVNNNA 448
              || .|..|..|.:|..|::         :||...|...:.|:
  Rat   361 --GLGTRCCHRHQPRHDSHSH---------LRLTTVSTLCDRNS 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tmA_capaR	108..399	CDD:320262	121/321 (38%)
		TM helix 1	108..135	CDD:320262	15/28 (54%)
		TM helix 2	142..168	CDD:320262	18/25 (72%)
		TM helix 3	181..211	CDD:320262	13/29 (45%)
		TM helix 4	223..245	CDD:320262	7/21 (33%)
		TM helix 5	265..294	CDD:320262	13/28 (46%)
		TM helix 6	316..346	CDD:320262	15/39 (38%)
		TM helix 7	367..392	CDD:320262	9/24 (38%)
Nmur1	XP_017452122.1	7tm_GPCRs	50..356	CDD:475119	121/319 (38%)
		TM helix 1	52..76	CDD:410628	14/23 (61%)
		TM helix 2	85..107	CDD:410628	14/21 (67%)
		TM helix 3	124..146	CDD:410628	7/21 (33%)
		TM helix 4	169..185	CDD:410628	6/15 (40%)
		TM helix 5	218..241	CDD:410628	8/22 (36%)
		TM helix 6	285..307	CDD:410628	10/21 (48%)
		TM helix 7	324..349	CDD:410628	9/24 (38%)