Protein Alignment PK2-R1 and CCHa2-R

DIOPT Version :10

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001356958.1
• Gene: CCHa2-R / 35535
• FlyBaseID: FBgn0033058
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 132/518 - (25%)
• Similarity: 217/518 - (41%)
• Gaps: 115/518 - (22%)

  Fly    88 GTNASTMAADSP----VDESLTLRTALTVCYALIFVAGVLGNLITCIVISRNNFMHTATNFYLFN 148
            |.|||......|    :|...|.  .:||.|.|||:.|||||....|:..|:..|....|.|:.:
  Fly    48 GHNASADGGIVPYVPVLDRPETY--IVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILS 110

  Fly   149 LAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHP 213
            ||::||::::..:|.... ::..:.:||...||.:.....:::...:|.|:||.:.|||.||.:|
  Fly   111 LALADLLVILVCVPVATI-VYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNP 174

  Fly   214 FRQHTMSKLSRAIKFIFA---IWLAAFLLALPQAMQFSVVYQNEGYSCT----------MENDFY 265
            .|     ||......:|.   ||:.|.||.:|..: ||.:.....::.|          ..:..|
  Fly   175 LR-----KLQTKPLTVFTAVMIWILAILLGMPSVL-FSDIKSYPVFTATGNMTIEVCSPFRDPEY 233

  Fly   266 AHVFAVSG--FIFFGGPMTAICVLYVLIGVKLKRSRLLQSLP--RRTFDANRGLNAQGRVIRMLV 326
            |. |.|:|  .:::..|::.|..||:::..:|..|  .:::|  :::..:.....|:..|.||:|
  Fly   234 AK-FMVAGKALVYYLLPLSIIGALYIMMAKRLHMS--ARNMPGEQQSMQSRTQARARLHVARMVV 295

  Fly   327 AVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIM 391
            |..|.||:|:.|:|      |:.|.......:.:.|::::.:|........||::|:||:....:
  Fly   296 AFVVVFFICFFPYH------VFELWYHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCV 354

  Fly   392 SHKFREAFK-----ITLTRQFGLARNHHHQQSQHHQHNYSALLRQNGSMRLQPASCSVNNNALEP 451
            |..||:.|.     |.:.||..|           .||:.:..:..|.|:.....|..|...|
  Fly   355 SGVFRQHFNRYLCCICVKRQPHL-----------RQHSTATGMMDNTSVMSMRRSTYVGGTA--- 405

  Fly   452 YGSYRVVQFRCRDANHQLSLQDSIRTTTTTTTINSNSMAAGNGVGGGAGGGGGGRRLRKQEL--- 513
             |:.|....  |::||.:.                   .||.|||||.|.|..|...|:..:
  Fly   406 -GNLRASLH--RNSNHGVG-------------------GAGGGVGGGVGSGRVGSFHRQDSMPLQ 448

  Fly   514 ----YGPGPGTAVPHRMLQAQVSQLSSLGDANSLLEAEVVDRHYASGRAKRALLATKSGALLV 572
                :|.|.|            ...|.||               |.||. .|:...: |.|:|
  Fly   449 HGNAHGGGAG------------GGSSGLG---------------AGGRT-AAVSEKRXGTLIV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tmA_capaR	108..399	CDD:320262	84/307 (27%)
		TM helix 1	108..135	CDD:320262	12/26 (46%)
		TM helix 2	142..168	CDD:320262	7/25 (28%)
		TM helix 3	181..211	CDD:320262	9/29 (31%)
		TM helix 4	223..245	CDD:320262	7/24 (29%)
		TM helix 5	265..294	CDD:320262	9/30 (30%)
		TM helix 6	316..346	CDD:320262	12/29 (41%)
		TM helix 7	367..392	CDD:320262	6/24 (25%)
CCHa2-R	NP_001356958.1	7tmA_Bombesin_R-like	70..362	CDD:320593	84/309 (27%)
		TM helix 1	71..97	CDD:320593	12/25 (48%)
		TM helix 2	104..130	CDD:320593	7/26 (27%)
		TM helix 3	142..172	CDD:320593	9/29 (31%)
		TM helix 4	182..202	CDD:320593	6/19 (32%)
		TM helix 5	234..259	CDD:320593	8/25 (32%)
		TM helix 6	285..315	CDD:320593	14/35 (40%)
		TM helix 7	330..355	CDD:320593	6/24 (25%)