Protein Alignment PK2-R1 and Ghsr

DIOPT Version :10

• Sequence 1: NP_731790.1
• Gene: PK2-R1 / 41639
• FlyBaseID: FBgn0038140
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_017175002.1
• Gene: Ghsr / 208188
• MGIID: 2441906
• Length: 427
• Species: Mus musculus
• Alignment Length: 411
• Identity: 138/411 - (33%)
• Similarity: 189/411 - (45%)
• Gaps: 72/411 - (17%)

  Fly    24 AHVSP--SPNQSPSIGVGIGIASSTM--------------ANPSESPEMLLLKNDKFLTHVAHLL 72
            ||.||  :|..:|::....|....|.              |.|||.||.
Mouse    27 AHSSPHAAPRPAPTLPRLGGPPQGTRFPRGCDPKPGNMWNATPSEEPEP---------------- 75

  Fly    73 NITTENLSNLLGSTNGTNASTMAADSPVDESLTLRTA------LTVCYALIFVAGVLGNLITCIV 131
            |:|.:    |....:..|      ||..||.|.|..|      ...|.|| ||.|:.|||:|.:|
Mouse    76 NVTLD----LDWDASPGN------DSLSDELLPLFPAPLLAGVTATCVAL-FVVGISGNLLTMLV 129

  Fly   132 ISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATV 196
            :||...:.|.||.||.::|.|||::.:. :|.:|..||....:.|.|.:|.:...:||....|||
Mouse   130 VSRFRELRTTTNLYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATV 193

  Fly   197 LTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGYSCTME 261
            |||||.:||||.|||.|.|...:....|....|..||..||..|.|..:...|.::| |......
Mouse   194 LTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHEN-GTDPRDT 257

  Fly   262 NDFYAHVFAV-SGF---------IFFGGPMTAICVLYVLIGVKLKRSRLLQSLPRRTFDANRGLN 316
            |:..|..||| ||.         :||..|:..:.|||.|||.||.|.|...::.....|.|
Mouse   258 NECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGSSLRDQN---- 318

  Fly   317 AQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLST 381
             ..:.::||..|..||.|||.|||..|.:........::.|::  .:.|..::.:   ||::||.
Mouse   319 -HKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQ--ISQYCNLVSF---VLFYLSA 377

  Fly   382 CINPLLYNIMSHKFREA-FKI 401
            .|||:||||||.|:|.| ||:
Mouse   378 AINPILYNIMSKKYRVAVFKL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R1	NP_731790.1	7tmA_capaR	108..399	CDD:320262	112/307 (36%)
		TM helix 1	108..135	CDD:320262	13/32 (41%)
		TM helix 2	142..168	CDD:320262	10/25 (40%)
		TM helix 3	181..211	CDD:320262	16/29 (55%)
		TM helix 4	223..245	CDD:320262	8/21 (38%)
		TM helix 5	265..294	CDD:320262	15/38 (39%)
		TM helix 6	316..346	CDD:320262	12/29 (41%)
		TM helix 7	367..392	CDD:320262	11/24 (46%)
Ghsr	XP_017175002.1	7tmA_GHSR	107..395	CDD:320259	110/300 (37%)
		TM helix 1	107..133	CDD:320259	12/26 (46%)
		TM helix 2	140..165	CDD:320259	10/25 (40%)
		TM helix 3	178..208	CDD:320259	16/29 (55%)
		TM helix 4	220..242	CDD:320259	8/21 (38%)
		TM helix 5	271..300	CDD:320259	9/28 (32%)
		TM helix 6	317..347	CDD:320259	13/34 (38%)
		TM helix 7	363..388	CDD:320259	12/27 (44%)