Protein Alignment PK2-R2 and gpr39

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_956711.2
• Gene: gpr39 / 791773
• ZFINID: ZDB-GENE-040426-1395
• Length: 440
• Species: Danio rerio
• Alignment Length: 456
• Identity: 125/456 - (27%)
• Similarity: 200/456 - (43%)
• Gaps: 81/456 - (17%)

  Fly    46 QGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLIT---CIVISRNNFMHTATNFYLFN 107
            |.|||.           ..|...|:|.|.||...|||||..|   ..|:.||.::..:...::.:
Zfish    11 QQLEPS-----------YGLKVFLTVLYCLILSLGVLGNSATIHVAQVLQRNGYLQRSVAEHMVS 64

  Fly   108 LAISDMILLCSGMPQDLYN-LWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICH 171
            ||.||:::|..|:|.:||: :|.|......|:.|.:.:.|.|..:.||:|.:...::|||:||||
Zfish    65 LACSDLLVLLIGLPVELYSAIWFPFLSRSGDAACRIYNFLFELCSYATILNVATLSLERYLAICH 129

  Fly   172 PFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQF----------SVVMQGMGTSCTMKNDFFAH 226
            |||...: :..|..:.:.|.|:.:.|:|||..:..          ...:|.: |.||..:..:.
Zfish   130 PFRYRAL-RGGRTRRLLLAAWLCSALVALPLLVATGTEGYVPAGRQTPVQNL-TFCTSLSQHWV- 191

  Fly   227 VFAVSGFLFFGGPMTAICVLYVLI--GVKLKRSRLLQAL-----PRRC-------YDVNRGISAQ 277
            ::..|.|..|        |||:|:  ||......::..|     |...       :...||.:::
Zfish   192 MYRTSIFTAF--------VLYLLVLAGVAFMCRAMILVLRAPMGPAEAGASGDHKHQSARGKASR 248

  Fly   278 TRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGI-ESQWFNDVFSI---LDYTSGVLYFLSTC 338
            .:.|..||.:..|.|:||.|...:|||     |:.: :|.|.....:.   |...:...::||:.
Zfish   249 KQTILFLVLIVCALFVCWMPNQIRRLM-----TAAVPKSSWTGSYLTSYIKLHPVADSFFYLSSV 308

  Fly   339 INPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPHTYSALRRNQT------GSL-RLHTTDS 396
            :||:|||:.|.:||.||..||.....|...|: |.|.::.::...|.|      .|| |:....|
Zfish   309 LNPMLYNLSSRQFRSAFLQTLLCRLSLQHANR-RTLENSGASKSSNNTLRPLLQRSLNRIRMATS 372

  Fly   397 VRTTMTSMATTTTGLNGSANGSGNGTTTGQSVRLNRVSLDSVQM----QGQNRSRQDLFDNPRRM 457
            .|:|..|.|.....||.:....|.|          :::||....    ||:.....|..:..|..
Zfish   373 SRSTPPSSAERRDSLNTTDRPQGEG----------KLTLDPQNTTNWPQGEGELTSDSQEKERNQ 427

  Fly   458 L 458
            |
Zfish   428 L 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	91/317 (29%)
		TM helix 1	69..94	CDD:320262	12/27 (44%)
		TM helix 2	101..127	CDD:320262	9/26 (35%)
		TM helix 3	140..170	CDD:320262	10/29 (34%)
		TM helix 4	182..204	CDD:320262	7/21 (33%)
		TM helix 5	225..253	CDD:320262	8/29 (28%)
		TM helix 6	275..305	CDD:320262	10/29 (34%)
		TM helix 7	323..348	CDD:320262	8/27 (30%)
gpr39	NP_956711.2	7tmA_GPR39	21..325	CDD:320263	91/319 (29%)
		TM helix 1	21..48	CDD:320263	11/26 (42%)
		TM helix 2	58..84	CDD:320263	9/25 (36%)
		TM helix 3	98..128	CDD:320263	10/29 (34%)
		TM helix 4	139..161	CDD:320263	7/21 (33%)
		TM helix 5	190..219	CDD:320263	9/37 (24%)
		TM helix 6	246..276	CDD:320263	11/34 (32%)
		TM helix 7	293..318	CDD:320263	8/24 (33%)