DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK2-R2 and Ntsr2

DIOPT Version :9

Sequence 1:	NP_731788.1	Gene:	PK2-R2 / 41638	FlyBaseID:	FBgn0038139	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_073186.1	Gene:	Ntsr2 / 64636	RGDID:	70962	Length:	416	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	105/375 - (28%)
Similarity:	163/375 - (43%)	Gaps:	80/375 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 PTVTPMTPLSLLATLSVG------------YALIFIAGVLGNLITC-IVISRNNFMHTATNFYLF 106
            |..:|...|||.|.|.|.            |:|||..|..||.::. :|:...........:::.
  Rat     9 PRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFAFGTAGNALSVHVVLKARAGRPGRLRYHVL 73

  Fly   107 NLAISDMILLCSGMPQDLYN-LWHPDNYP--FSDSICILESVLSETAANATVLTITAFTVERYIA 168
            :||:|.::||...||.:||| :|  .:||  |.|..|.....:.|..|.||||::.:.:.||.:|
  Rat    74 SLALSALLLLLVSMPMELYNFVW--SHYPWVFGDLGCRGYYFVRELCAYATVLSVASLSAERCLA 136

  Fly   169 ICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAI---QFSVVMQGMGTS------CTMKND-- 222
            :|.|.|...:....|..:.:..:|:|:|.||||.|:   |...|....|..      ||:...
  Rat   137 VCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEVESADGEPEPASRVCTVLVSRA 201

  Fly   223 ------------FFAHVFAVSGFLFFGGPMTAICVLYV-----------------------LIGV 252
                        .||...|::.|| .|..:..:..||.                       |:|.
  Rat   202 TLQVFIQVNVLVSFALPLALTAFL-NGITVNHLMALYSQVPSASAQVSSIPSRLELLSEEGLLGF 265

  Fly   253 KLKRSRL---LQALPRRCYDVN--RGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSG 312
            ...|..|   :||...|..|.:  |.:....:|:|.:|||   :.|||.|:||:|||..|....|
  Rat   266 ITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLRAIVAV---YVICWLPYHARRLMYCYIPDDG 327

  Fly   313 IESQWFNDVFSILDY---TSGVLYFLSTCINPLLYNIMSHKFREAFKVTL 359
                |.|:::....|   .:..|:::|:.:.|:|||.:|..||:.|..:|
  Rat   328 ----WTNELYDFYHYFYMVTNTLFYVSSAVTPILYNAVSSSFRKLFLESL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	84/318 (26%)
Ntsr2	NP_073186.1	7tm_1	87..358	CDD:278431	76/280 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020