Protein Alignment PK2-R2 and Nmur2

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_071611.3
• Gene: Nmur2 / 64042
• RGDID: 621155
• Length: 395
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 121/342 - (35%)
• Similarity: 193/342 - (56%)
• Gaps: 39/342 - (11%)

  Fly    30 LTQVLNISADNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRN 94
            |.:.||.:.:.|..|......:..||             :||.|||||:.||:|||:.|:||.|:
  Rat    14 LMKYLNSTEEYLAHLCGPKRSDLSLP-------------VSVAYALIFLVGVMGNLLVCMVIVRH 65

  Fly    95 NFMHTATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYP--FSDSICILESVLSETAANATVLT 157
            ..:.|.||:|||:||:||:::|..|||.::|.:||  |||  |....|..::.|.||...|::|:
  Rat    66 QTLKTPTNYYLFSLAVSDLLVLLLGMPLEIYEMWH--NYPFLFGPVGCYFKTALFETVCFASILS 128

  Fly   158 ITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALP----QAIQFSVVMQGM----G 214
            :|..:||||:||.||||....|...||::.:..:|..:::.:||    ..|:|.....|.    .
  Rat   129 VTTVSVERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSSVPGS 193

  Fly   215 TSCTMKNDFFAH--VFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRLLQALPRRCYDVNRGISAQ 277
            .:||:....:.:  :...:.|||:..|||.|.|||.|:|::|||...|:| .:...:::|  .::
  Rat   194 ATCTVTKPMWVYNLIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEA-NKVAVNIHR--PSR 255

  Fly   278 TRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFND---VFSILDYTSGVLYFLSTCI 339
            ..|.:||..:.:.|.|||.|||..||.     .|.:| :|...   ||:::...|||.::||:.:
  Rat   256 KSVTKMLFVLVLVFAICWTPFHVDRLF-----FSFVE-EWTESLAAVFNLIHVVSGVFFYLSSAV 314

  Fly   340 NPLLYNIMSHKFREAFK 356
            ||::||::|.:||.||:
  Rat   315 NPIIYNLLSRRFRAAFR 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	112/300 (37%)
		TM helix 1	69..94	CDD:320262	15/24 (63%)
		TM helix 2	101..127	CDD:320262	14/25 (56%)
		TM helix 3	140..170	CDD:320262	12/29 (41%)
		TM helix 4	182..204	CDD:320262	5/25 (20%)
		TM helix 5	225..253	CDD:320262	12/29 (41%)
		TM helix 6	275..305	CDD:320262	12/29 (41%)
		TM helix 7	323..348	CDD:320262	9/24 (38%)
Nmur2	NP_071611.3	7tm_GPCRs	38..330	CDD:475119	114/315 (36%)
		TM helix 1	40..64	CDD:410628	15/23 (65%)
		TM helix 2	73..95	CDD:410628	12/21 (57%)
		TM helix 3	112..134	CDD:410628	6/21 (29%)
		TM helix 4	157..173	CDD:410628	2/15 (13%)
		TM helix 5	206..229	CDD:410628	9/22 (41%)
		TM helix 6	259..281	CDD:410628	9/21 (43%)
		TM helix 7	298..323	CDD:410628	9/24 (38%)
		NmU-R2_C_term	323..389	CDD:466027	5/9 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..395