DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK2-R2 and ntsr1

DIOPT Version :9

Sequence 1:NP_731788.1 Gene:PK2-R2 / 41638 FlyBaseID:FBgn0038139 Length:599 Species:Drosophila melanogaster
Sequence 2:XP_021329279.1 Gene:ntsr1 / 569344 ZFINID:ZDB-GENE-090313-372 Length:400 Species:Danio rerio


Alignment Length:423 Identity:130/423 - (30%)
Similarity:198/423 - (46%) Gaps:91/423 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 LTQVLNISA-------DNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLIT 87
            |.|.|..||       ||.|..|.    ||.|...|.:....|:..:   |.::|:.|.|||.||
Zfish    17 LAQKLLSSANRSQPFLDNETESLS----EEDLDVNTDIYSKVLVTVI---YVVLFLIGCLGNSIT 74

  Fly    88 CIVI----SRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYN-LW--HPDNYPFSDSICILESV 145
            ...:    |..|...| .:::|.:|||||:::|...||.:||| :|  ||  :.|.:::|.....
Zfish    75 LYTLLTKKSLQNLQST-VHYHLASLAISDLLILVLCMPIELYNFIWVHHP--WAFGEAVCKGYYF 136

  Fly   146 LSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFSVVM 210
            |.:..:.||...|.:.:|||::||||||:..::...||..|.|.|:|||:..||.|  :.|::..
Zfish   137 LRDGCSYATAFNIASLSVERFMAICHPFKAKSIMSRSRTKKLISAMWIASFFLATP--MLFTMGQ 199

  Fly   211 QGMG---------TSCTMKNDFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKR---------- 256
            |.|.         :|.|.|.     |..::.||.|..||..|..|..:|..:|.|          
Zfish   200 QLMNDEYICTTIVSSITAKT-----VLQLNAFLSFVVPMALISALNGVIASQLLRMFRESAQDNR 259

  Fly   257 --------SRLLQAL-PRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSG 312
                    :.|..|: |.|...:..|       :.:|.||.:||.:||.|:||:|||..|     
Zfish   260 VCIIGGNATMLSVAVEPNRAQSMRHG-------VMVLRAVVIAFVVCWLPYHARRLMYCY----- 312

  Fly   313 IESQWFNDVFSILDY---TSGVLYFLSTCINPLLYNIMSHKFREAFKVTL------ARHFGLGGK 368
             .::|...::....|   .:.||:::|:.|||:|||::|..:|:.|..||      .||     |
Zfish   313 -VTEWTTALYDFYHYFYMVTNVLFYVSSAINPILYNLVSANYRQIFFSTLRYLILPCRH-----K 371

  Fly   369 NQGRGLPHTYSALRRNQTGSLRLHTTDSVRTTM 401
            .|.|.|.....::..|||.|     |:.::.|:
Zfish   372 KQKRVLTRHSISICSNQTFS-----TNVIKETI 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK2-R2NP_731788.1 7tm_1 83..344 CDD:278431 92/298 (31%)
ntsr1XP_021329279.1 7tmA_NTSR1 54..357 CDD:320477 102/328 (31%)
TM helix 1 54..81 CDD:320477 9/29 (31%)
TM helix 2 91..117 CDD:320477 11/25 (44%)
TM helix 3 131..161 CDD:320477 9/29 (31%)
TM helix 4 173..195 CDD:320477 11/23 (48%)
TM helix 5 217..246 CDD:320477 10/33 (30%)
TM helix 6 280..310 CDD:320477 13/36 (36%)
TM helix 7 325..350 CDD:320477 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.020

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