Protein Alignment PK2-R2 and nmur-2

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_493666.2
• Gene: nmur-2 / 173398
• WormBaseID: WBGene00019616
• Length: 403
• Species: Caenorhabditis elegans
• Alignment Length: 387
• Identity: 125/387 - (32%)
• Similarity: 187/387 - (48%)
• Gaps: 68/387 - (17%)

  Fly    53 LLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLC 117
            ::|||             :.|..||:.|:.||:.|||||:.|..||..||:|||:||:||:|.|.
 Worm    31 VIPTV-------------IIYGTIFLLGLFGNICTCIVIAANKSMHNPTNYYLFSLAVSDIIALI 82

  Fly   118 SGMPQDLY-NLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKL 181
            .|:|.:.| :|.:...|.||:.||...:.|.|..:.|:::.|..|:.||::|||||.|....|.|
 Worm    83 LGLPMEFYQSLDYSYPYRFSEGICKARAFLIEFTSYASIMIICCFSFERWLAICHPLRSKIFSTL 147

  Fly   182 SRAVKFIFAIWIAALLLALPQA--IQFSVV-------MQGMGTSCTMKNDFFAH----------- 226
            .||...|...|..:.:.|||.|  :|.:.:       .|......:....|..|
 Worm   148 WRANVLIILAWTISFVCALPIAFIVQINKLPLPEDAKYQPWTNKVSTDGIFVLHTEFCAMNQSRP 212

  Fly   227 -------VFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRL----LQALPRRCYDVNRGISAQTRV 280
                   :||.:  :||..|..||.::|..|.|:|:.|.:    .:.:.:|....||      .|
 Worm   213 DQQKMIIIFAFT--VFFVIPAIAIVIMYAHIAVQLESSEIDLKGDKMVKKRRNKSNR------TV 269

  Fly   281 IRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDVFSILD----YTSGVLYFLSTCINP 341
            ::||::|.:.|||||.|||.|||::||  |:..|:...:.....|.    |.||..|:.::..||
 Worm   270 LKMLLSVVITFFICWLPFHIQRLLSVY--TTWSETTTISPPVQFLSMIVFYISGFCYYSNSAANP 332

  Fly   342 LLYNIMSHKFREAF-KVTLARHFG----LGGKNQGRGLPHTYSALRRNQTGSLRLHTTDSVR 398
            :||||:|.|:|.|| :..|..|..    .|.:..|:....:.|.....:|    |.|..|||
 Worm   333 ILYNILSQKYRSAFCRTILGDHIANFVFKGHQRPGQSKRCSSSTEAEQRT----LMTRGSVR 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	109/321 (34%)
		TM helix 1	69..94	CDD:320262	11/24 (46%)
		TM helix 2	101..127	CDD:320262	14/26 (54%)
		TM helix 3	140..170	CDD:320262	9/29 (31%)
		TM helix 4	182..204	CDD:320262	8/23 (35%)
		TM helix 5	225..253	CDD:320262	10/45 (22%)
		TM helix 6	275..305	CDD:320262	15/29 (52%)
		TM helix 7	323..348	CDD:320262	11/28 (39%)
nmur-2	NP_493666.2	7tmA_capaR	32..346	CDD:320262	112/336 (33%)
		TM helix 1	32..59	CDD:320262	14/39 (36%)
		TM helix 2	66..92	CDD:320262	14/25 (56%)
		TM helix 3	106..136	CDD:320262	9/29 (31%)
		TM helix 4	148..170	CDD:320262	7/21 (33%)
		TM helix 5	215..244	CDD:320262	9/30 (30%)
		TM helix 6	264..294	CDD:320262	17/35 (49%)
		TM helix 7	314..339	CDD:320262	10/24 (42%)