DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK2-R2 and LOC101732366

DIOPT Version :9

Sequence 1:	NP_731788.1	Gene:	PK2-R2 / 41638	FlyBaseID:	FBgn0038139	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_004918724.1	Gene:	LOC101732366 / 101732366	-ID:	-	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	92/354 - (25%)
Similarity:	161/354 - (45%)	Gaps:	58/354 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVI--SRNNFMHTATNF 103
            :||....:.|....|.......:...:::|:.|.|:..||:|||.:...|:  .|...:..:.:.
Frog     1 MTSTTSSMPPVSKPPEAEVRLSIYAKSSISLTYMLLLFAGILGNAMVIRVLWGLRRRRVQASLSH 65

  Fly   104 YLFNLAISDMILLCSGMPQDLY-NLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYI 167
            ::.:||..|::.|..|:|.:|| ::|.|..:|..:..|.....|.|....|.:..:.:.:.||::
Frog    66 HMCSLASCDLLQLVLGIPAELYGSIWSPFPWPLGNIGCCGFYYLWEVLCYAAIFNVLSLSCERHL 130

  Fly   168 AICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGMGTS-----------CT--- 218
            |.|.|...| :.:.|..::..| ||:.:||..||  :.|::.::.:..:           ||
Frog   131 ATCRPLSLH-LRQSSVRLRLCF-IWLMSLLAGLP--VLFTMGLEDVYAADVDDQHTELWVCTPLS 191

  Fly   219 -MKNDFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKRSR------------------LLQALP 264
             .|..|.|.::|  .||.:.|.::       ::|:...|.|                  .:|.|.
Frog   192 SRKGLFVATIWA--SFLTYLGVLS-------VVGITCWRMRRALQGSASQDVEVAGPGGSVQLLG 247

  Fly   265 RRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDVFS---ILD 326
            |.|  ..:.::|:.:..|||..:..|..:||.||.|:|||.|..|    :.||..:.:.   .|.
Frog   248 RFC--SGQTVTARKQNARMLGCIVGALAVCWLPFQARRLMTVLRS----KDQWTENYYRSYITLQ 306

  Fly   327 YTSGVLYFLSTCINPLLYNIMSHKFREAF 355
            ..:...|:||:|:.|||||:.|..||.||
Frog   307 PITNCFYYLSSCLTPLLYNLTSQSFRRAF 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	74/299 (25%)
LOC101732366	XP_004918724.1	7tm_GPCRs	27..335	CDD:391938	86/326 (26%)
		TM helix 1	29..53	CDD:341315	9/23 (39%)
		TM helix 2	64..86	CDD:341315	6/21 (29%)
		TM helix 3	104..126	CDD:341315	3/21 (14%)
		TM helix 4	147..163	CDD:341315	7/18 (39%)
		TM helix 5	194..217	CDD:341315	7/31 (23%)
		TM helix 6	259..284	CDD:341315	9/24 (38%)
		TM helix 7	303..328	CDD:341315	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920