Protein Alignment PK2-R2 and ntsr2

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_017949971.1
• Gene: ntsr2 / 101730337
• XenbaseID: XB-GENE-22068810
• Length: 430
• Species: Xenopus tropicalis
• Alignment Length: 430
• Identity: 115/430 - (26%)
• Similarity: 202/430 - (46%)
• Gaps: 101/430 - (23%)

  Fly    61 TPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHT---ATNFYLFNLAISDMILLCSGMPQ 122
            |..|....::|.|.|||:.|.:||::|..::.:.:..|.   ..:::|.::|:||:::|...:|.
 Frog    31 THFSSKVFITVFYILIFLVGTIGNVLTIRLVLKKHNRHKLQGTVHYHLVSMALSDILILLISIPI 95

  Fly   123 DLYN-LWHPDNYP--FSDSICILESVLSETAANATVLTITAFTVERYIAICHPF-RQHTMSKLSR 183
            :||| :|  .:||  |.|::|.....|.:..:.||||.||:.:.|||:|||||. .:..|||: |
 Frog    96 ELYNFIW--VHYPWIFGDAVCRSYYFLRDICSYATVLNITSLSCERYLAICHPMTAKRIMSKM-R 157

  Fly   184 AVKFIFAIWIAALLLALPQA----IQF------------SVVMQGMGTSCTMKNDFFAHVF-AVS 231
            ..|.:..||.::::.|:|.|    :::            |::...:.::.|:|      || .|:
 Frog   158 TKKILSVIWFSSVVFAMPMAFIMGVKYENTTPEGEEDPSSLICTNLVSTATLK------VFIQVN 216

  Fly   232 GFLFFGGPMTAI-CVLYVLIG-VKLKRSRLLQAL------PRRCYDVN---RGISAQTRV----- 280
            .|:.|..|:..| |:..|.:. ::..|||...:|      |:..|..:   :.:|:...|
 Frog   217 VFVSFLLPLALISCLNCVTVNQLESLRSRYFLSLHSSSKAPQASYRAHVSLKPVSSSPAVKKLSV 281

  Fly   281 ------------------------IRMLVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDV 321
                                    |.||.|:.:|:.:||.|:||:|||..|..    :..|...:
 Frog   282 AGATSKSSLTVSCEPNRIQPIQHSIYMLRAIVIAYVVCWLPYHARRLMFCYIP----DDYWTGFL 342

  Fly   322 FSILDY---TSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPHTYSALRR 383
            ::...|   .:..|:::|:.:||:|||::|..|||.|..||.                 :|..|:
 Frog   343 YTFYHYFYMLTNTLFYVSSAVNPILYNMVSSSFRELFLETLG-----------------FSRRRK 390

  Fly   384 NQ--TGSLRLHTTDSVRTTMTSMATTTTGLNGSANGSGNG 421
            .|  ..|:.|.|  |:|:...::.|.|.....|...:.||
 Frog   391 EQQLNSSVSLQT--SLRSDTCTLHTPTNHRQASREETANG 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	97/352 (28%)
		TM helix 1	69..94	CDD:320262	9/24 (38%)
		TM helix 2	101..127	CDD:320262	9/26 (35%)
		TM helix 3	140..170	CDD:320262	12/29 (41%)
		TM helix 4	182..204	CDD:320262	7/25 (28%)
		TM helix 5	225..253	CDD:320262	9/30 (30%)
		TM helix 6	275..305	CDD:320262	14/58 (24%)
		TM helix 7	323..348	CDD:320262	8/27 (30%)
ntsr2	XP_017949971.1	7tm_GPCRs	36..379	CDD:475119	97/355 (27%)
		TM helix 1	38..63	CDD:410628	9/24 (38%)
		TM helix 2	75..97	CDD:410628	6/21 (29%)
		TM helix 3	115..137	CDD:410628	7/21 (33%)
		TM helix 4	160..176	CDD:410628	4/15 (27%)
		TM helix 5	210..233	CDD:410628	9/28 (32%)
		TM helix 6	306..328	CDD:410628	10/21 (48%)
		TM helix 7	347..372	CDD:410628	8/24 (33%)