Protein Alignment PK2-R2 and nmur2

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_002940961.1
• Gene: nmur2 / 100498226
• XenbaseID: XB-GENE-6046084
• Length: 397
• Species: Xenopus tropicalis
• Alignment Length: 316
• Identity: 114/316 - (36%)
• Similarity: 181/316 - (57%)
• Gaps: 28/316 - (8%)

  Fly    63 LSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYNL 127
            |||..||.  ||.||:.||:||.:.|:||.:::.|.|.||:|||:||:||:::|..|||.::|.:
 Frog    43 LSLPMTLV--YATIFLIGVIGNTLVCLVILKHHNMRTPTNYYLFSLAVSDLLVLLLGMPLEVYEM 105

  Fly   128 WHPDNYPFSDSI--CILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFA 190
            |  .||||....  |..::||.||...|::|::|..:||||:||.|||:....|..|||:|.:..
 Frog   106 W--SNYPFLFGAWGCYFKTVLFETVCFASILSVTTVSVERYVAIIHPFQAKLKSTRSRALKILVT 168

  Fly   191 IWIAALLLALPQAIQFSVVMQGM--------GTSCTMKNDFFAH--VFAVSGFLFFGGPMTAICV 245
            :||.::|.::|......:::|..        ..:||:....:.:  :..|:..||:..||..|.|
 Frog   169 LWIFSILFSIPNTSTHGILLQYFPNGSLIPDSATCTVVQPLWIYNCIIQVTSLLFYILPMGVISV 233

  Fly   246 LYVLIGVKLKRSRLLQALPRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYGST 310
            ||.|:|:||:....|:| .:...:|.|  .::..:.:||..:.:.|.|||||||..||...:
 Frog   234 LYCLMGIKLRGDHSLEA-DKMSVNVQR--PSRKSITKMLFVLVMVFGICWAPFHVDRLFFSF--- 292

  Fly   311 SGIESQW---FNDVFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHF 363
               ...|   ..:.|::....|||.::||:.:|||:||::|.:||.||:..|...|
 Frog   293 ---VLDWTEPLANAFNLTHVVSGVFFYLSSAVNPLIYNLLSRRFRSAFQNVLPPFF 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	106/300 (35%)
		TM helix 1	69..94	CDD:320262	12/24 (50%)
		TM helix 2	101..127	CDD:320262	14/25 (56%)
		TM helix 3	140..170	CDD:320262	13/29 (45%)
		TM helix 4	182..204	CDD:320262	8/21 (38%)
		TM helix 5	225..253	CDD:320262	11/29 (38%)
		TM helix 6	275..305	CDD:320262	12/29 (41%)
		TM helix 7	323..348	CDD:320262	10/24 (42%)
nmur2	XP_002940961.1	7tmA_NMU-R2	45..337	CDD:320479	108/304 (36%)
		TM helix 1	45..72	CDD:320479	14/28 (50%)
		TM helix 2	79..105	CDD:320479	14/25 (56%)
		TM helix 3	118..148	CDD:320479	13/29 (45%)
		TM helix 4	160..182	CDD:320479	8/21 (38%)
		TM helix 5	212..241	CDD:320479	11/28 (39%)
		TM helix 6	260..290	CDD:320479	12/29 (41%)
		TM helix 7	305..330	CDD:320479	10/24 (42%)
		NmU-R2_C_term	330..397	CDD:466027	7/16 (44%)