Protein Alignment PK2-R2 and ghsrb

DIOPT Version :10

• Sequence 1: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_002666717.1
• Gene: ghsrb / 100332193
• ZFINID: ZDB-GENE-090327-1
• Length: 365
• Species: Danio rerio
• Alignment Length: 361
• Identity: 123/361 - (34%)
• Similarity: 177/361 - (49%)
• Gaps: 43/361 - (11%)

  Fly    35 NISADNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHT 99
            ||...|.||       |:..|  ..:.|:.:|..::|..:.:|:.|:.|||:|.:|:::...|.|
Zfish    20 NIMDSNATS-------EDEYP--VHLFPVPILTGITVTCSFLFLVGIAGNLLTILVVTKYKDMRT 75

  Fly   100 ATNFYLFNLAISD-MILLCSGMPQDLYNLWHPDNYPFSDSICILESVLSETAANATVLTITAFTV 163
            .||.||.::|:|| :|.||  ||.|||.:|....:.|.|.:|.|...:||:...:|:|.|||.:|
Zfish    76 TTNLYLCSMALSDLLIFLC--MPLDLYRVWRYRPWNFGDELCKLFQFVSESCTYSTILNITALSV 138

  Fly   164 ERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGMGTSCTMKNDFFAHVF 228
            |||.|||.|.|...:....|....|..:|..||..|.|..|...|..:. ||:....|:..|..:
Zfish   139 ERYFAICFPLRAKVIVTRGRVKGVILLLWTVALCSAGPIFILVGVEHEN-GTNAWETNECKATEY 202

  Fly   229 AV-SGFL---------FFGGPMTAICVLYVLIGVKLKRSRLLQALPRRCYDVNRGISAQTRVIRM 283
            |: ||.|         ||..|:..:.|||.|||.:|.|.:.....|....|     .:..:.::|
Zfish   203 AIRSGLLTMMVWVSSVFFFLPVLCLTVLYSLIGRRLWRRKENPVGPISSRD-----KSNKQTVKM 262

  Fly   284 LVAVAVAFFICWAPFHAQRLMAVYGSTSGIESQWFNDVFSILDYTSGVLYFLSTCINPLLYNIMS 348
            |..|.:||.:||.|||..|.:.  ..:|...|...:.:....:..|.||::||..|||:||||||
Zfish   263 LAVVVLAFVLCWLPFHVGRYLV--SKSSEANSPVISQISEYCNLVSFVLFYLSAAINPILYNIMS 325

  Fly   349 HKFREA----FKVTLARHFGLGGKNQGRGLPHTYSA 380
            .|||.|    |:|..|         .||.|....:|
Zfish   326 KKFRSAACKLFRVKRA---------PGRSLQSIVNA 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	107/300 (36%)
		TM helix 1	69..94	CDD:320262	8/24 (33%)
		TM helix 2	101..127	CDD:320262	15/26 (58%)
		TM helix 3	140..170	CDD:320262	14/29 (48%)
		TM helix 4	182..204	CDD:320262	7/21 (33%)
		TM helix 5	225..253	CDD:320262	14/37 (38%)
		TM helix 6	275..305	CDD:320262	11/29 (38%)
		TM helix 7	323..348	CDD:320262	12/24 (50%)
ghsrb	XP_002666717.1	7tm_GPCRs	43..332	CDD:475119	106/298 (36%)
		TM helix 1	45..69	CDD:410628	8/23 (35%)
		TM helix 2	78..99	CDD:410628	11/22 (50%)
		TM helix 3	116..138	CDD:410628	8/21 (38%)
		TM helix 4	161..177	CDD:410628	5/15 (33%)
		TM helix 5	209..232	CDD:410628	6/22 (27%)
		TM helix 6	260..282	CDD:410628	10/21 (48%)
		TM helix 7	300..325	CDD:410628	12/24 (50%)