Protein Alignment wntD and WNT5B

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_110402.2
• Gene: WNT5B / 81029
• HGNCID: 16265
• Length: 359
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 83/304 - (27%)
• Similarity: 129/304 - (42%)
• Gaps: 54/304 - (17%)

  Fly    41 GKGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSPNREDVYVAAISMAAIVHTLTKDCANG 105
            |:|.|..:..||..|:.:||||.:.|......:..:.. :||..:..|:|.|.:|:.:::.|..|
Human    73 GEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIG-SRETAFTHAVSAAGVVNAISRACREG 136

  Fly   106 VIAGCGCTENAL---------------NVPCAHEPTKAL---EQYEKHFGSGSGAIGH------- 145
            .::.|||:..|.               ||...:...|..   .:.||:|..||...|.
Human   137 ELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQN 201

  Fly   146 ---NRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAI------ 201
               .||.|    .:..:..|:|.   .|.|.|..:.|...|..|..:...|.:.||.|.
Human   202 NEAGRRAV----YKMADVACKCH---GVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTR 259

  Fly   202 --QLEGASSNLKIMWQNIPLDSLVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEERLSCQQ 264
              :||..:|...   |..|.| ||::..||:||.|:.:....||:||.|:|...|    ...|:.
Human   260 KGRLELVNSRFT---QPTPED-LVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEG----MDGCEL 316

  Fly   265 LCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
            :|...||. :.:.|:.| ||:||..|...::|..|.::..||.|
Human   317 MCCGRGYN-QFKSVQVE-RCHCKFHWCCFVRCKKCTEIVDQYIC 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	83/304 (27%)
WNT5B	NP_110402.2	Wnt_Wnt5b	48..359	CDD:381722	83/304 (27%)