Protein Alignment wntD and WNT10A

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_079492.2
• Gene: WNT10A / 80326
• HGNCID: 13829
• Length: 417
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 87/338 - (25%)
• Similarity: 129/338 - (38%)
• Gaps: 97/338 - (28%)

  Fly    42 KGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSP-----NREDVYVAAISMAAIVHTLTKD 101
            :|::.|:..||..|:.|||||.|.:  .:|..|.| ||     .||..:..||:.|.:||.::..
Human    87 QGIQIAIHECQHQFRDQRWNCSSLE--TRNKIPYE-SPIFSRGFRESAFAYAIAAAGVVHAVSNA 148

  Fly   102 CANGVIAGCGC------TENAL--------------------NVPCAHE--PTKA---------- 128
            ||.|.:..|||      .|.|.                    .|| .|.  ||.:
Human   149 CALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLSHGVP-EHPALPTASPGLQDSWEWG 212

  Fly   129 ----------------LEQYEKHFGSGSGAIGHNRRVVGALLQRSLEQECRCKQPGAVQGECQEE 177
                            |:..|.|....:....||.||....:..::.::|:|.   ...|.||.:
Human   213 GCSPDMGFGERFSKDFLDSREPHRDIHARMRLHNNRVGRQAVMENMRRKCKCH---GTSGSCQLK 274

  Fly   178 ECVAVLKPFEAIAQDLLQMYDDAI----------QLE-----------GASSNLKIMWQNIPLDS 221
            .|..|...|..:...|...:..|.          |||           ||....:   :..|.|
Human   275 TCWQVTPEFRTVGALLRSRFHRATLIRPHNRNGGQLEPGPAGAPSPAPGAPGPRR---RASPAD- 335

  Fly   222 LVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEERLSCQQLCRVCGYRVRSQHVRTERRCNC 286
            ||:.:.||::|||:......||.||.|:|..:||    ..|..:|...|:.:..| .|:| ||:|
Human   336 LVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGS----DGCGSMCCGRGHNILRQ-TRSE-RCHC 394

  Fly   287 KLVWGFRLQCDVC 299
            :..|...:.|:.|
Human   395 RFHWCCFVVCEEC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	87/338 (26%)
WNT10A	NP_079492.2	Wnt	58..417	CDD:393294	87/338 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..331		5/33 (15%)