Protein Alignment wntD and WNT2B

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 79/305 - (25%)
• Similarity: 124/305 - (40%)
• Gaps: 59/305 - (19%)

  Fly    41 GKGLKQALDSCQQSFQWQRWNCPSQD-------FVQKNSKPEENSPNREDVYVAAISMAAIVHTL 98
            |:|.::.:..||..|:..||||.:.|       .|...|       :||..:|.|||.|.:||.:
Human    97 GEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRS-------SREAAFVYAISSAGVVHAI 154

  Fly    99 TKDCANGVIAGC--------------------GCTENALNVPCAHEPTKALEQY----EKHFGSG 139
            |:.|:.|.::.|                    ||::|      .|...:..:.:    ||.....
Human   155 TRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDN------IHYGVRFAKAFVDAKEKRLKDA 213

  Fly   140 SGAIG-HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQL 203
            ...:. ||.|.....::|.|:.||:|.   .|.|.|....|...|..|......|.:.||.|:|:
Human   214 RALMNLHNNRCGRTAVRRFLKLECKCH---GVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQV 275

  Fly   204 ----EGAS-SNLKIMWQNIPLDSLVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEERLSCQ 263
                :||: :..:..::......||:..:||:||..|......||.||.|||...|:    ..|:
Human   276 MATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGT----DGCE 336

  Fly   264 QLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
            .:|  ||....:..|....:|.||..|...::|..|......::|
Human   337 IMC--CGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTC 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	79/305 (26%)
WNT2B	NP_078613.1	Wnt_Wnt2b	67..380	CDD:381720	79/305 (26%)
		WNT-core domain	107..379		76/293 (26%)