Protein Alignment wntD and WNT11

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: XP_011543540.1
• Gene: WNT11 / 7481
• HGNCID: 12776
• Length: 364
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 83/310 - (26%)
• Similarity: 129/310 - (41%)
• Gaps: 66/310 - (21%)

  Fly    45 KQALDSCQQSFQWQRWNCPSQDF-------VQKNSK--PEENSPNREDVYVAAISMAAIVHTLTK 100
            ::.:.:|:::|...||||.|.:.       :::.|.  |...|..||..:|.|:|.|||.|.:.:
Human    74 REVMKACRRAFADMRWNCSSIELAPNYLLDLERASADLPLPPSGTRESAFVYALSAAAISHAIAR 138

  Fly   101 DCANGVIAGC-----------------GCTEN-----ALNVPCAHEPTKALEQYEKHFGSGSGAI 143
            .|.:|.:.||                 ||.:|     .:....:..|.|.     |..||.:..:
Human   139 ACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKV-----KKTGSQANKL 198

  Fly   144 G--HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQL--- 203
            .  ||..|....|:.|||.:|:|.   .|.|.|....|...|:..:.:|.||...|..|.::
Human   199 MRLHNSEVGRQALRASLEMKCKCH---GVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHR 260

  Fly   204 -EGASSNLKIMWQNIPLD---------SLVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEE 258
             .|...:|      :|.|         .||::|.||::|.::......||:.|||:|..:||
Human   261 PMGTRKHL------VPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGS--- 316

  Fly   259 RLSCQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
             .||..:|  ||........|...||:||..|...:.|..|.:...:|.|
Human   317 -DSCDLMC--CGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	83/310 (27%)
WNT11	XP_011543540.1	Wnt_Wnt11	51..364	CDD:381717	83/310 (27%)