Protein Alignment wntD and WNT4

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: XP_011539899.1
• Gene: WNT4 / 54361
• HGNCID: 12783
• Length: 373
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 82/307 - (26%)
• Similarity: 131/307 - (42%)
• Gaps: 57/307 - (18%)

  Fly    38 DITGKGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSPNREDVYVAAISMAAIVHTLTKDC 102
            |...:|.:.|::.||..|:.:||||.:.|.:....|..... .||..:|.|||.|.:...:|:.|
Human    87 DSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQG-TREAAFVYAISSAGVAFAVTRAC 150

  Fly   103 ANGVIAGCGCTENALNVP--------CAHE-------PTKALEQYEKHFG-SGSGAIG--HNRRV 149
            ::|.:..|||......|.        |:..       ....::..|:..| |.|.|:.  ||...
Human   151 SSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEA 215

  Fly   150 VGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQLE----GASSNL 210
            ....:...:..||:|.   .|.|.|:.:.|...:.||..:...|.:.:|.|.::|    |:|..|
Human   216 GRKAILTHMRVECKCH---GVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRAL 277

  Fly   211 KIMWQNIPL---------DSLVFMQDSPNYCERDATGLWKGTRGRQCSK-----DGSGSLEERLS 261
                  :|.         :.||:::.||::||:|......|||||.|:|     ||
Human   278 ------VPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDG--------- 327

  Fly   262 CQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
            |:.||  ||....:..|....||:||..|...::|..|.:|...::|
Human   328 CELLC--CGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTC 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	82/307 (27%)
WNT4	XP_011539899.1	Wnt_Wnt4	65..373	CDD:381710	82/307 (27%)