Protein Alignment wntD and WNT16

DIOPT Version :10

• Sequence 1: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_476509.1
• Gene: WNT16 / 51384
• HGNCID: 16267
• Length: 365
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 76/311 - (24%)
• Similarity: 124/311 - (39%)
• Gaps: 62/311 - (19%)

  Fly    42 KGLKQALDSCQQSFQWQRWNC---PSQDFVQKNSKP----EENSPNREDVYVAAISMAAIVHTLT 99
            :|.:..:..|...|:.:||||   .:.......:.|    |.:|..:|..::.|:..|.:||::|
Human    72 EGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSVT 136

  Fly   100 KDCANGVIAGCGCTENALNVPCAHEPTKALEQYEKHFGSGSG---------------AIG----- 144
            :.|:.|.:..|.|.....|...|.|..        |:|..|.               .||
Human   137 RSCSAGNMTECSCDTTLQNGGSASEGW--------HWGGCSDDVQYGMWFSRKFLDFPIGNTTGK 193

  Fly   145 ----------HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDD 199
                      ||.......:.:.:..:|||.   .|.|.|..:.|...:..||.|...|...|::
Human   194 ENKVLLAMNLHNNEAGRQAVAKLMSVDCRCH---GVSGSCAVKTCWKTMSSFEKIGHLLKDKYEN 255

  Fly   200 AIQLEGASSNLKIM-----WQNIPL--DSLVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLE 257
            :||:...:.. |:.     .:.||:  |.|:::..|||||..|......||:||:|::...|:
Human   256 SIQISDKTKR-KMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGA-- 317

  Fly   258 ERLSCQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308
              ..|..||  ||....:..||...||.||.:|...::|..|..:...::|
Human   318 --DGCNLLC--CGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTC 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	76/311 (24%)
WNT16	NP_476509.1	Wnt_Wnt16	52..365	CDD:381718	76/311 (24%)