DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11668 and svh-1

DIOPT Version :9

Sequence 1:	NP_650254.1	Gene:	CG11668 / 41606	FlyBaseID:	FBgn0038113	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	260	Identity:	67/260 - (25%)
Similarity:	114/260 - (43%)	Gaps:	45/260 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 LVGGRLTQENEHPYMCALGWPSRTNRWIHEHGSSKRRYTFNCGCAMIAPRFAITAAHCASVGGES 212
            :|||..|.....|:..||              .:|.....:||.:::.....||||||.......
Worm   713 VVGGFETVPGAFPWTAAL--------------RNKATKAHHCGASILDKTHLITAAHCFEEDERV 763

  Fly   213 PSVALIGGVELNS---GRGQLIEIKRISQHPHFDAETLTNDLAVVKLA------RRSHMPVACLW 268
            .|..::.|...|:   |..|:..::||..:|.: .:..::|:|::::.      .....|: ||.
Worm   764 SSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLY-KDIFSHDIAILEIPYPGIEFNEYAQPI-CLP 826

  Fly   269 NQESL--PERPLTALGYGQ--TKFAGPHSSNLLQIMLYHLNFQQCQRYLHNYDKLANGLGSGQMC 329
            :::.:  |.|.....|:|.  .::|....:.|:.|    :|...|.    |..::.:.:.....|
Worm   827 SKDFVYTPGRQCVVSGWGSMGLRYAERLQAALIPI----INRFDCV----NSSQIYSSMSRSAFC 883

  Fly   330 AGDYSGNMDTCQGDSGGPLLLHQHMRHHRHTIPYVV-GITSFGGACA-SGQPGVYVRIAHYIQWI 392
            ||...|.:|:||||||||...      .|....:|: |:.|:|..|| ..|||:|..:|.|:.||
Worm   884 AGYLEGGIDSCQGDSGGPFAC------RREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWI 942

Fly 393 392
Worm 943 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11668	NP_650254.1	Tryp_SPc	149..395	CDD:238113	67/259 (26%)
CG11668	NP_650254.1	Tryp_SPc	149..392	CDD:214473	65/257 (25%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	67/260 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100