DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11668 and F9

DIOPT Version :9

Sequence 1:	NP_650254.1	Gene:	CG11668 / 41606	FlyBaseID:	FBgn0038113	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	393	Identity:	88/393 - (22%)
Similarity:	155/393 - (39%)	Gaps:	114/393 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GKCVRYVDCISAMQAVPRVTPLLCPSSWPNQLVCCPHGGYLLPPPSISKSEQACANAYP----RA 113
            |:|.::                 |.:|..|:::|....||     .:::.:::|....|    ||
Mouse   139 GRCKQF-----------------CKNSPDNKVICSCTEGY-----QLAEDQKSCEPTVPFPCGRA 181

  Fly   114 ----HHKRRRRRRNTNPKLDQVELVEPI--------------IQKHNQSQN---LLVGGRLTQEN 157
                ..|:..|.......:|.....|.:              :.:.::|.|   .:|||    ||
Mouse   182 SISYSSKKITRAETVFSNMDYENSTEAVFIQDDITDGAILNNVTESSESLNDFTRVVGG----EN 242

  Fly   158 EHPYMCALGWPSRTNRWIHEHGSSKRRYTFNCGCAMIAPRFAITAAHCASVGGESPSVALIGGVE 222
            ..|..  :.|....|..|...          ||.|:|..::.:|||||...|.:   :.::.| |
Mouse   243 AKPGQ--IPWQVILNGEIEAF----------CGGAIINEKWIVTAAHCLKPGDK---IEVVAG-E 291

  Fly   223 LNSGRGQLIEIKR--ISQHPHFDAETLTN----DLAVVKLAR----RSHMPVACLWNQESLPERP 277
            .|..:.:..|.:|  |...||.......|    |:|:::|.:    .|::...|:.|:|
Mouse   292 YNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANRE------ 350

  Fly   278 LTAL----------GYGQTKFAGPHSSNLLQIMLYHLNFQQCQR----YLHNYDKLANGLGSGQM 328
            .|.:          |:|:....|..:|.|..:.:..::...|.|    .::|          ...
Mouse   351 YTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFTIYN----------NMF 405

  Fly   329 CAGDYSGNMDTCQGDSGGPLLLHQHMRHHRHTIPYVVGITSFGGACA-SGQPGVYVRIAHYIQWI 392
            |||...|..|:|:||||||     |:.....| .::.||.|:|..|| .|:.|:|.:::.|:.||
Mouse   406 CAGYREGGKDSCEGDSGGP-----HVTEVEGT-SFLTGIISWGEECAMKGKYGIYTKVSRYVNWI 464

  Fly   393 EQQ 395
            :::
Mouse   465 KEK 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11668	NP_650254.1	Tryp_SPc	149..395	CDD:238113	70/270 (26%)
CG11668	NP_650254.1	Tryp_SPc	149..392	CDD:214473	68/267 (25%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342	8/52 (15%)
		Tryp_SPc	236..464	CDD:214473	68/269 (25%)
		Tryp_SPc	237..467	CDD:238113	70/271 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910