Protein Alignment Su(fu) and Sufu

DIOPT Version :10

• Sequence 1: NP_536750.2
• Gene: Su(fu) / 41565
• FlyBaseID: FBgn0005355
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001020070.1
• Gene: Sufu / 361769
• RGDID: 1559462
• Length: 485
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 188/523 - (35%)
• Similarity: 263/523 - (50%)
• Gaps: 110/523 - (21%)

  Fly     1 MAEANLDKKPEVKP--------------------PPGLKAIIDHLGQVYPNQPNPLQVTTLLKYW 45
            |||.    :|.|.|                    ||||.||.....::||:||||||||.::|||
  Rat     1 MAEL----RPSVAPGPAAPPASGPSAPPAFASLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYW 61

  Fly    46 LGGQDPLDYISMYNYPGDVDRNVPPHWHYISFGLSDLHGDERVHLREEGVTRSGMGFELTFRLAK 110
            |||.|||||:|||...|....|:|.||||||||||||:||.|||........||.||||||||.:
  Rat    62 LGGPDPLDYVSMYRNMGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKR 126

  Fly   111 TEIELKQQIENPEKPQRPPTWPANLLQAIGRYCFQTGNGLCFGDNIPWRKSLDGSTTSKLQNLLV 175
            ...|           ..||||||.|:|.:.||.||:.|..|.||::.|...||.| .|::|::|:
  Rat   127 ETGE-----------SAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNS-ESRIQHMLL 179

  Fly   176 AQDPQLGCIDTPTGTVDFCQIVGVFDDELEQASRWNGRGVLNFLRQDMQTGGDWLVTNMDRQMSV 240
            .:|||:..:.||.|.|.|.|||||..:||..|.:|||:|:|..||.....||.||:|:|.|..::
  Rat   180 TEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETI 244

  Fly   241 FELFPETLLNLQDD-----LEKQGSDLAGVNADFTFRELKPTKEVKEEVDFQALSEKCANDENNR 300
            ||:.|    :||.:     :|..||:|:||:|...:.:|....|               :||::|
  Rat   245 FEIDP----HLQQERVDKGIETDGSNLSGVSAKCAWDDLSRPPE---------------DDEDSR 290

  Fly   301 QL-----------TDTQMKRE----------EPSFPQSMSMSSNSL--------HKSCPLDFQ-A 335
            .:           .||:..||          :|..|...|...|.|        ..|...|.. |
  Rat   291 SICLGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINSQRQNGLTYDRAPSRKDSLGSDISTA 355

  Fly   336 QAPNCI----SLDGIEITLAPGVAKYLLLAIKDRIRHGRHFTFKA--QHLALTLVAESVTGSAVT 394
            ..|:.:    .|:.:.:.........:.|.::.|:.||||||:|:  ..:|:|.|:..|.|:..|
  Rat   356 VIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFAT 420

  Fly   395 VNEPYGVLGYWIQVLIPDELVPRLMEDFRSAGLDEKCEPKE-RL--ELEWPDKNLK------LII 450
            ...||...|.|:|:|:.:|.|.:::||     |::...|:| :|  |..||:|.||      ::.
  Rat   421 EEHPYAAHGPWLQILLTEEFVEKMLED-----LEDLTSPEEFKLPKEYSWPEKKLKVSILPDVVF 480

  Fly   451 DQP 453
            |.|
  Rat   481 DSP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(fu)	NP_536750.2	SUFU	48..237	CDD:461543	92/188 (49%)
		SUFU_C	250..450	CDD:463598	63/249 (25%)
Sufu	NP_001020070.1	SUFU	64..240	CDD:461543	92/187 (49%)
		SUFU_C	254..474	CDD:463598	61/239 (26%)