DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11600 and LIPK

DIOPT Version :10

Sequence 1:NP_650217.2 Gene:CG11600 / 41555 FlyBaseID:FBgn0038068 Length:406 Species:Drosophila melanogaster
Sequence 2:XP_011538375.1 Gene:LIPK / 643414 HGNCID:23444 Length:419 Species:Homo sapiens


Alignment Length:399 Identity:118/399 - (29%)
Similarity:213/399 - (53%) Gaps:21/399 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 WLLIVSGMPKVKFGLQNFTGRGKDYRIKVITGI-LIIDKYGYSVETHTVRTGDGYILDMFRIPSS 75
            |:|::..|    :|   :..:|.:...:....| .||..:||..|.:.|.|.|||||.::|||..
Human    30 WMLLLGSM----YG---YDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHG 87

  Fly    76 PNCK-EDGFKPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYDVWLSNSRGVRYSQRHIRLKA 139
            ..|. ....||:|.:|||||:.|.:::...|.:.|.|:|||..|||||.||||..:|::|::|..
Human    88 RGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSP 152

  Fly   140 SQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTTLLVLLSMKPEYNRMIKTANM 204
            ....:|.||..||...||||.|::|:..|.::.|::|.||||.|...:..|..||..:.||....
Human   153 KSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFA 217

  Fly   205 MAPAVFMKHARN---KLMKMFGNIIMSMKDSSFFGPLDAI-RFLLSVFCKCSKFKKLCA-FMFIL 264
            :||.|.:|:.::   ||..:...::..:.....|.|.... :|:.:..|....|:::|: |:|.|
Human   218 LAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTL 282

  Fly   265 ASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYDFGVM-RNKKLYNQDTPPDY 328
            :..:|.: :|.:.:.:.|:.:|...|.:...|:.|...||:.:.:|:|.. :|...::|.|||.|
Human   283 SGFDPQN-LNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLY 346

  Fly   329 PLENVRPQSPIHIYHSHGDDLVA-RKDIHILISKLDKAVLHDVVFEKWSHSDFLFAKLIKKVVNE 392
            .:  .:.:.|..|::. |.|:|| .||:..|:.::...:.:.:: ..::|.||...:...:.:.:
Human   347 NI--TKMEVPTAIWNG-GQDIVADPKDVENLLPQIANLIYYKLI-PHYNHVDFYLGEDAPQEIYQ 407

  Fly   393 PIIKVIDHF 401
            .:|.:::.:
Human   408 DLIILMEEY 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11600NP_650217.2 PLN02872 46..396 CDD:215470 111/357 (31%)
LIPKXP_011538375.1 PLN02872 31..410 CDD:215470 116/390 (30%)

Return to query results.
Submit another query.