DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18549 and CG3078

DIOPT Version :9

Sequence 1:	NP_650203.3	Gene:	CG18549 / 41538	FlyBaseID:	FBgn0038053	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	86/516 - (16%)
Similarity:	154/516 - (29%)	Gaps:	208/516 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SLAIIYLFFSLSNWLAPSFISFT----GPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLG 110
            ||.:..||...:....||.....    ||.:  |...:|...|:::.::.|...|.....:||:
  Fly   294 SLLLSALFLVAAGMSLPSIRLMKRYGYGPLI--VANYMTVLLFLLSHLYASIYTLLPAYLLLGM- 355

  Fly   111 ASITWTGQGTYLARCSESSTISRNSGV-------FWALLQCS------------------MFIGN 150
                               |:|.::|.       |...|.||                  ||...
  Fly   356 -------------------TLSGSAGSKAALIVHFGGKLSCSCDSQQSQAAVDVLHEEHKMFCNR 401

  Fly   151 LFVYYQFQDKTRIDKETRNL-----------VIGVLTVIAVL-------------GIVFLA---- 187
                         |::.|.|           :||...:.::|             |:|:..
  Fly   402 -------------DQKVRRLARWFRVSQDLGLIGGALLASILLACSDGNFTGDCSGLVYYGNESW 453

  Fly   188 --ALRFMADNAEHDNELEQKHTGCG-----------------------QAIYA--LKS----AGQ 221
              .||...:..||.:.:      ||                       .:|||  ::|    |||
  Fly   454 PPQLRDFYNRNEHGDRI------CGADMCPLRVQSILEAGWANGSSIPSSIYAGFIESEPRVAGQ 512

  Fly   222 ----LFLTKKMLLLSLAF----------------------------------FYTGLELSFFSGV 248
                |::...|:.|:|:.                                  ::.|.|.::..|.
  Fly   513 SLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSRPERSRDVSITDTLLFAGPLAYFVGTEQAYMMGD 577

  Fly   249 FGSAIGFTTKIAETPKEIVGLVGICIGAGEVFGGGLFGILGNKT-----TRYGRDPIVIAGYVMH 308
            |..|.            :...:||.:.||.:.|.||..::.:.|     ....|..:::||:..|
  Fly   578 FLRAF------------VTCSLGIGMIAGALIGMGLMQLIVSCTLSMLLRHVKRIVVILAGFFFH 630

  Fly   309 MAAFFMTFINLPNSAPFKDTTDISYLDPPRASIALVCAFLLGLGDACFNTQIYSML---GGEYVN 370
            ..    ..:.|.:..|..|.:.:.|          |.|...|..:..:.|.:.|::   ...:|.
  Fly   631 SC----LLLALSSWKPSSDDSALFY----------VIAASWGACNGMWETLLLSLVTLNHSSHVT 681

  Fly   371 NAVGAFALFKFTQSVAAAISFFYSSHFGLYVQLGI--LVVMGTIGTIAFVFVEWGFKRQHR 429
            .........:|     ..:...::.|..|...:.|  |||:..|....:..:|...:.|.:
  Fly   682 EVQAPLLALRF-----LGLGLTFAGHGFLCESMKIIALVVLLVISVPPYATLEIRLEAQRK 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18549	NP_650203.3	MFS_MFSD11	8..423	CDD:340965	85/508 (17%)
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	47/265 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910