DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18549 and AgaP_AGAP000311

DIOPT Version :9

Sequence 1:	NP_650203.3	Gene:	CG18549 / 41538	FlyBaseID:	FBgn0038053	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_310812.3	Gene:	AgaP_AGAP000311 / 1271951	VectorBaseID:	AGAP000311	Length:	435	Species:	Anopheles gambiae

Alignment Length:	430	Identity:	245/430 - (56%)
Similarity:	316/430 - (73%)	Gaps:	8/430 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ILILGFGFMFVFTAFQTMCNIEKTILDSISQEDDTFKGEGYTSLAIIYLFFSLSNWLAPSFISFT 72
            :|:||.|||.:||:|||:.|||:||:|||.::..:|.|:|||||||||...|||||:.||.:|..
Mosquito     9 VLLLGGGFMLIFTSFQTLGNIEQTIIDSIKKDLPSFTGDGYTSLAIIYAALSLSNWVTPSVLSAI 73

  Fly    73 GPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLGASITWTGQGTYLARCSESSTISRNSGV 137
            |||:|||:||:||..||.:|..|...|||..|.|||.||::.|||||.||::||...|||||||:
Mosquito    74 GPRLAMVIGAITYCLFMASFFVPHVALLYGCSVVLGAGAALIWTGQGMYLSQCSSGDTISRNSGI 138

  Fly   138 FWALLQCSMFIGNLFVYYQFQDKTRIDKETRNLVIGVLTVIAVLGIVFLAALRFMADNAEHDNEL 202
            |||:||.|||.|||.|::.||.||.||:.||::|..||..:.::|:|||..||  ..:|..|..:
Mosquito   139 FWAMLQMSMFFGNLLVFFTFQGKTHIDETTRSIVFAVLIAVGIVGLVFLTCLR--RPSASGDAPV 201

  Fly   203 EQKHTGCGQAIYALKSAGQLFLTKKMLLLSLAFFYTGLELSFFSGVFGSAIGFTTKIAETPKEIV 267
            |..|:  .:...|..:|.:||.|.:|:|||:.|.||||.|||||||:||:||||..|..:.|:.|
Mosquito   202 ELSHS--VEPRQAFLNAIRLFQTPRMILLSITFVYTGLSLSFFSGVYGSSIGFTNAIGTSAKQYV 264

  Fly   268 GLVGICIGAGEVFGGGLFGILGNK-TTRYGRDPIVIAGYVMHMAAFFMTFINLPNSAPFKDTTDI 331
            ||.|:.||.|||.||..||:||.: |||:|||||||||.|:||||:|:.::||||:|||.:|..:
Mosquito   265 GLNGVFIGVGEVLGGVAFGLLGTRTTTRWGRDPIVIAGGVLHMAAYFLIYLNLPNAAPFGNTDAL 329

  Fly   332 SYLDPPRASIALVCAFLLGLGDACFNTQIYSMLGGEYVNNAVGAFALFKFTQSVAAAISFFYSSH 396
            ||:.||.|.:|:.|:|||||||||||||.||||||.:.:....||::||||||||||.||.|||:
Mosquito   330 SYIQPPSALVAMGCSFLLGLGDACFNTQCYSMLGGVFKSQPAEAFSIFKFTQSVAAAASFVYSSY 394

  Fly   397 FGLYVQLGILVVMGTIGTIAFVFVEWGFKRQHREQEALEK 436
            .||:|||.||||:|.||||.|..||:..|   ||:..||:
Mosquito   395 CGLHVQLLILVVLGIIGTITFCVVEFAVK---RERPTLER 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18549	NP_650203.3	MFS_MFSD11	8..423	CDD:340965	240/415 (58%)
AgaP_AGAP000311	XP_310812.3	MFS	12..166	CDD:304372	93/153 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	280	1.000	Domainoid score	I4126
eggNOG	1	0.900	-	-		E1_KOG3098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11517
Inparanoid	1	1.050	478	1.000	Inparanoid score	I3235
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D338483at33208
OrthoFinder	1	1.000	-	-		FOG0002381
OrthoInspector	1	1.000	-	-		oto108727
Panther	1	1.100	-	-	LDO	PTHR23294
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1405
TreeFam	1	0.960	-	-
	13	12.940