DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha2 and psma2b

DIOPT Version :9

Sequence 1:	NP_524328.1	Gene:	Prosalpha2 / 41531	FlyBaseID:	FBgn0086134	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_001122146.1	Gene:	psma2b / 403015	ZFINID:	ZDB-GENE-060503-941	Length:	234	Species:	Danio rerio

Alignment Length:	233	Identity:	184/233 - (78%)
Similarity:	209/233 - (89%)	Gaps:	0/233 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATERYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRV 65
            ||...||||||||||||||||:|||||||:.|||||||.||||||:|||.|.||.||::.|||:|
Zfish     1 MAERGYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHKV 65

  Fly    66 EMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRPF 130
            |.|..||||||||||||||:||::|||:||.|:|.|:||||..|||||||::|||||||||||||
Zfish    66 EPITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQSGGVRPF 130

  Fly   131 GVSLLICGWDNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDDAVHTAILTL 195
            ||||||.|||.|||||:|||||||||||||||||||.|||||||||||:|||||:||:|||||||
Zfish   131 GVSLLIAGWDEDRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTL 195

  Fly   196 KEGFEGKMTADNIEIGICDQNGFQRLDPASIKDYLASI 233
            ||.|||:||.||||:|||::.||:||.||.:|||||:|
Zfish   196 KESFEGQMTEDNIEVGICNEAGFRRLSPAEVKDYLAAI 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	179/224 (80%)
psma2b	NP_001122146.1	proteasome_alpha_type_2	6..231	CDD:239719	179/224 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578408
Domainoid	1	1.000	305	1.000	Domainoid score	I1343
eggNOG	1	0.900	-	-		E1_KOG0181
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2081
Inparanoid	1	1.050	381	1.000	Inparanoid score	I2021
OMA	1	1.010	-	-		QHG54016
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003690
OrthoInspector	1	1.000	-	-		otm26345
orthoMCL	1	0.900	-	-		OOG6_101969
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810