DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosalpha2 and Prosbeta2R1

DIOPT Version :9

Sequence 1:	NP_524328.1	Gene:	Prosalpha2 / 41531	FlyBaseID:	FBgn0086134	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	43/202 - (21%)
Similarity:	81/202 - (40%)	Gaps:	15/202 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 AVSGGAPSVGIIASNGVVIATENK-HKSPLYEQHSVHRVEMIYNHIGMVYSGMGPDYRLLVKQAR 91
            |:..|...||||..:||::..:.: .:.|:....:..::..:.:||....:|...|..::.....
  Fly    44 AIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTS 108

  Fly    92 KIAQTYYLTYKEPIPV---SQLVQRVATLMQEYTQSGGVRPFGVSLLICGWDNDRPYLYQSDPSG 153
            .....:.|..:..:||   |.:::|.....|.:        .|.:|::.|.|...|.||...|.|
  Fly   109 AELDLHRLNTERRVPVVCASMMLRRTLFRYQGH--------IGAALVMGGVDTTGPQLYCIYPCG 165

  Fly   154 AYFAWKATAMGKNAVNGKTFLEKRYSEDLELDDAVHTAILTLKEG-FEGKMTADNIEIGICDQNG 217
            :.......|||...:...:.||..:..||:|:.........:..| |....:..||::.:....|
  Fly   166 SNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITAKG 230

  Fly   218 --FQRLD 222
              :.|.|
  Fly   231 AVYLRTD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	43/202 (21%)
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	42/198 (21%)
		proteasome_beta_type_7	49..236	CDD:239732	39/194 (20%)
		Pr_beta_C	241..274	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940