Protein Alignment Prosalpha2 and PSMA8

DIOPT Version :10

• Sequence 1: NP_524328.1
• Gene: Prosalpha2 / 41531
• FlyBaseID: FBgn0086134
• Length: 234
• Species: Drosophila melanogaster
• Sequence 2: NP_653263.2
• Gene: PSMA8 / 143471
• HGNCID: 22985
• Length: 256
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 97/243 - (39%)
• Similarity: 144/243 - (59%)
• Gaps: 20/243 - (8%)

  Fly     5 RYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIY 69
            ||..::|.|||.|.|.|:|||..||..|:.:|||..:|.||:..|.|..:.|.::.:|.::..:.
Human     4 RYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALD 68

  Fly    70 NHIGM------VYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVR 128
            :|:.|      ::.|:..|.|:::.:||...|::.||.::|:.|..:.:.:|||.|:||||.|.|
Human    69 DHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRR 133

  Fly   129 PFGVSLLICGWDNDR-PYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDD--AVHT 190
            |||:|.||.|:|:|. ..|||:||||.|.||||.|:|::|...:.||||.|:||....|  |:..
Human   134 PFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKL 198

  Fly   191 AILTLKEGFE--GKMTADNIEIGICDQNGFQRLDPASIKD---YLASI 233
            ||..|.|..:  ||    |||:.|..:|  |.|...|.|:   |:..|
Human   199 AIKALLEVVQSGGK----NIELAIIRRN--QPLKMFSAKEVELYVTEI 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha2	NP_524328.1	proteasome_alpha_type_2	6..231	CDD:239719	95/238 (40%)
PSMA8	NP_653263.2	proteasome_alpha_type_7	5..219	CDD:239724	88/217 (41%)