Protein Alignment Sccpdh2 and SCCPDH

DIOPT Version :8

• Sequence 1: NP_650190.1
• Gene: Sccpdh2 / 41521
• FlyBaseID: FBgn0038038
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_057086.2
• Gene: SCCPDH / 51097
• HGNCID: 24275
• Length: 429
• Species: Homo sapiens
• Alignment Length: 433
• Identity: 166/434 (38%)
• Similarity: 259/434 (60%)
• Gaps: 28/434 (6%)

  Fly     9 IIFGASGFTGKYTVFEAV------SVLKGLQWGIAGRNQEKLQSVLREMGAK--SKTDLSQTPIV 65
            ::||||||||::...|..      .....|.|.:|||::||||.||.:...|  ..|..|:..|:
Human    11 VVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAALKLGRPTLSSEVGII 75

  Fly    66 IADVNNEASLLEMAKRCRILVNTAGPYRFFGERVVRACIEAGTHHVDVSGEPQYMETMQLRYHDL 130
            |.|:.|.|||.||||:..:::|..|||||:||.|::||||.|...:|:|||||::|.|||:||:.
Human    76 ICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHEK 140

  Fly   131 AKERGVYVISACGFDSIPADMGVTFVEKNFDGVVNSVENF--VHLGVKGGTKGTGSAALNTGTWE 193
            |.::|||:|.:.||||||||:||.:.....:|.:.:||:|  :|.|.:|       .:::.|||:
Human   141 AADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTIHSGPEG-------LSIHDGTWK 198

  Fly   194 SAIHAIANRSESVAIRRKLFPERLPNFHPALKSRSPLSRAAEVDNKVILPFPETDRSVVMRSQRF 258
            |||:...::|....:|.....:.:|...|.||.|.|:|...|:....| ||..:|.|||.|:||:
Human   199 SAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSI-PFMGSDVSVVRRTQRY 262

  Fly   259 LYELEKKRPVQMQAYMTYPSWFAASVVVLFASIIGI-MAKFSFGRQLLLKYPTVFSGGMASREGP 322
            |||..::.|||..||:|. ....:.:.::||.:..: ..:|..|||||:|:|..||.|..|::||
Human   263 LYENLEESPVQYAAYVTV-GGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSKQGP 326

  Fly   323 SEARMERSFFRMTMKATGWPKSEKLAETTDQYTSPPTKTLTVRVTGPNPGYGSTCVALLSTAKTI 387
            ::.:::.:.|.:|....|:      ::.|....:.|...:..:|.||..||.:|.:|::..|.|:
Human   327 TQKQIDAASFTLTFFGQGY------SQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAAMTL 385

  Fly   388 LNESDKMPGSGGVLPPGAAFRGTSLISELEKHEHGIKFEIVAN 430
            |:::..:|.:|||..|||||..|.||..|.|  |||:|.::::
Human   386 LSDASHLPKAGGVFTPGAAFSKTKLIDRLNK--HGIEFSVISS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sccpdh2	NP_650190.1	COG3268	7..416	CDD:225807	160/418 (38%)
		Sacchrp_dh_NADP	9..139	CDD:281434	64/138 (46%)
SCCPDH	NP_057086.2	COG3268	1..421	CDD:225807	165/427 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C141702025
eggNOG	1	0.900				E1_COG3268
Hieranoid	1	1.000
Homologene	1	1.000				H9334
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2659
Isobase	1	0.950		0	Normalized mean entropy	S4069
OMA	1	1.010
OrthoDB	1	1.010				D302978at33208
OrthoFinder	1	1.000				FOG0002132
OrthoInspector	1	1.000				T609752
orthoMCL	1	0.900				OOG5_128445
Panther	1	1.100			O	PTHR12286
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4081
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	15	14.750