Protein Alignment DNAlig3 and CDC9

DIOPT Version :9

• Sequence 1: NP_650187.2
• Gene: DNAlig3 / 41518
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_010117.1
• Gene: CDC9 / 851391
• SGDID: S000002323
• Length: 755
• Species: Saccharomyces cerevisiae
• Alignment Length: 622
• Identity: 169/622 - (27%)
• Similarity: 271/622 - (43%)
• Gaps: 74/622 - (11%)

  Fly    36 FRRICD---EIAGESSYLKKAERLQRFFEK--GSSGKGFKGDTVLWVQFLIPAANQRV-YNLQNK 94
            :..:|:   :|...||.|:.......||.|  ..|.|.....|.|::..|.|.....: ..|...
Yeast   148 YSEVCEVFNKIEAISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGEN 212

  Fly    95 ALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKHFAASKKLKPQ--KQSKLYLQEVEEMLLHLVE 157
            .|:|..|........|:.|..:..||:.|..    ..::.::|.  |...|.:.||.:.|..:.:
Yeast   213 LLMKTISETCGKSMSQIKLKYKDIGDLGEIA----MGARNVQPTMFKPKPLTVGEVFKNLRAIAK 273

  Fly   158 RTKEDEQ---TDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAF-------------GP 206
            ...:|.|   ..|::::.:....::.:..||.::..|||....:.:|.:.             .|
Yeast   274 TQGKDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVLISLSKALLLHDENREDSP 338

  Fly   207 D-------AYPAYQSSRDLVAIVEQFATKENKNYASSPVKKTKKTSSSAIQVMTPISPMLASPCK 264
            |       ...|.|..||....|..:....|.......:...|..:   ::...|:.||||.|.|
Yeast   339 DKDVPMDVLESAQQKIRDAFCQVPNYEIVINSCLEHGIMNLDKYCT---LRPGIPLKPMLAKPTK 400

  Fly   265 SVEDAFKKSPTGLY-SEIKYDGERVQIHKQGND--FKFFSRNLKPVVDH--KIRALKKYIPQAFP 324
            ::.:...:.....: ||.||||||.|:|.. ||  .:.:|||.:.:.:.  :|. :..:| |...
Yeast   401 AINEVLDRFQGETFTSEYKYDGERAQVHLL-NDGTMRIYSRNGENMTERYPEIN-ITDFI-QDLD 462

  Fly   325 GGGEMILDSEIILVDTDTGALLPFGSLGAHKKQTF----ANAAVCLFVFDCILYDGEDLTQLPFR 385
            ....:|||.|.:..|.|.|.:|||..|...|::..    ....||||.||.:.|:.|.|.....:
Yeast   463 TTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKVKVCLFAFDILCYNDERLINKSLK 527

  Fly   386 KRREILEQNIQPIKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLK---SPTSTYQPGK--R 445
            :|||.|.:..:.:....|.:.........||.......::.:.||:::|   .|.|.|:|.|  |
Yeast   528 ERREYLTKVTKVVPGEFQYATQITTNNLDELQKFLDESVNHSCEGLMVKMLEGPESHYEPSKRSR 592

  Fly   446 NWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDA 510
            ||||:||||| :| :.|:.||.||||:||.||:.||...||:|||:.....::|..|:.:|..|.
Yeast   593 NWLKLKKDYL-EG-VGDSLDLCVLGAYYGRGKRTGTYGGFLLGCYNQDTGEFETCCKIGTGFSDE 655

  Fly   511 TNAEVHKSLI-------KLTERADANAIPS-WLLCSKSLVPDVLAKDPMKMPVWEITGAEFTKSD 567
            ....:|..|.       |.|...|::|.|. |.  ..:.:.:||..|....|:::...|.|.|
Yeast   656 MLQLLHDRLTPTIIDGPKATFVFDSSAEPDVWF--EPTTLFEVLTADLSLSPIYKAGSATFDK-- 716

  Fly   568 AHTASGISVRFPRITRRRSDKSAKEANDLAHLEDLFE 604
                 |:|:||||..|.|.||..::|.....:.:|:|
Yeast   717 -----GVSLRFPRFLRIREDKGVEDATSSDQIVELYE 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	37/174 (21%)
		dnl1	88..604	CDD:273147	154/563 (27%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	69/225 (31%)
		OBF_DNA_ligase_III	460..598	CDD:153436	48/145 (33%)
CDC9	NP_010117.1	dnl1	215..748	CDD:273147	152/553 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810