Protein Alignment: DNAlig3 and Lig1

• Sequence 1: NP_650187.2
• Gene: DNAlig3
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001019439.1
• Gene: Lig1
• RGDID: 621424
• Length: 913
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 162/671 (24%)
• Similarity: 252/671 (38%)
• Gaps: 202/671 (30%)

  Fly    36 FRRICD--EIAGESSYLKKAERLQ-----------RFFEKGSSGKGFKGDTVLWVQFLIPAANQR 87
            |.:.||  .:.|.:|..||.:.::           ||..:..||:...|   |..|.::.|..|.
  Rat   400 FTKFCDIARLTGSASMAKKMDIIKGLFVACRYSEARFIARSLSGRLRLG---LAEQSVLAALAQA 461

  Fly    88 VYNLQNKALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKHFAASKKLKPQKQSKLYLQEVEEML 152
            |                         .|...|....|.   ...:.|.|..:..|::|
  Rat   462 V-------------------------SLTPPGQEFPTA---VVDAGKGKTAEARKMWL------- 491

  Fly   153 LHLVERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAFGPDAYPAYQSSRD 217
                     :||..:|::...:..||| |....|::|               |.::.|.:
  Rat   492 ---------EEQGMILKQTFCEVPDLD-RIIPVLLEH---------------GLESLPEH----- 526

  Fly   218 LVAIVEQFATKENKNYASSPVKKTKKTSSSAIQVMTPISPMLASPCKSVEDAFKK-SPTGLYSEI 281
                                         ..:....|:.||||.|.:.|.:..|: .......|.
  Rat   527 -----------------------------CKLSPGVPLKPMLAHPTRGVREVLKRFEEVDFTCEY 562

  Fly   282 KYDGERVQIH-KQGNDFKFFSRNLK------PVVDHKIRALKKYIPQAFPGGGEMILDSEIILVD 339
            ||||:|.||| .:|.:.|.||||.:      |.:..:|..:|      .|.....|||:|.:..|
  Rat   563 KYDGQRAQIHVLEGGEVKIFSRNQEDNSGKYPDIISRIPKIK------HPSVTSFILDTEAVAWD 621

  Fly   340 TDTGALLPFGSLGAHKKQ----TFANAAVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKS 400
            .:...:.||..|...|::    :.....|||:.||.|..:||.|.:.|..:||::|.:|....:.
  Rat   622 REKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLARQPLSRRRQLLRENFVETEG 686

  Fly   401 HVQLSESEFLKTTRELAAMTARVLHANLEGVVLKS--PTSTYQPGKR--NWLKVKKDYLFDGKMA 461
            ....:.|...|...::|....:.:..:.||:::|:  ..:||:..||  ||||:||||| :| :.
  Rat   687 EFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYL-EG-VG 749

  Fly   462 DTADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLT--- 523
            ||.||||:||:.|.||:.|....||:..||......:.:.|:.:|..|....|.|:|:..|.
  Rat   750 DTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSMQALLLPT 814

  Fly   524 ----ERADANAIPS-WLLCSKSLVPDVLAKDPMKMPVWEITGAEFTKSDAHTAS--------GIS 575
                .|.|....|. ||             ||  ..|||:..|:.:.|..:.|:        |||
  Rat   815 PRPYVRIDGAVAPDHWL-------------DP--SVVWEVKCADLSLSPIYPAARGLVDKEKGIS 864

  Fly   576 VRFPRITRRRSDKSAKEANDLAHLEDLFEASKSNVNVDLLLANCSKDETAMNNKTTPEKEKKLNG 640
            :||||..|.|.||..::|.....:..|:                             .|:.::..
  Rat   865 LRFPRFIRVREDKQPEQATTSDQVASLY-----------------------------RKQSQIQN 900

  Fly   641 NQSNGSKKLKRSNTGSDDED 660
            .||        |:..||.||
  Rat   901 QQS--------SDLDSDVED 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	33/177 (19%)
		dnl1	88..604	CDD:273147	138/548 (25%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	67/228 (29%)
		OBF_DNA_ligase_III	460..598	CDD:153436	48/154 (31%)
Lig1	NP_001019439.1	PLN03113	159..909	CDD:215584	159/666 (24%)
		DNA_ligase_A_N	283..454	CDD:282522	14/57 (25%)
		Adenylation_DNA_ligase_I_Euk	526..744	CDD:185710	67/258 (26%)
		OBF_DNA_ligase_I	749..894	CDD:153438	49/189 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910