Protein Alignment: DNAlig3 and lig3

• Sequence 1: NP_650187.2
• Gene: DNAlig3
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001025345.2
• Gene: lig3
• ZFINID: ZDB-GENE-030131-8453
• Length: 1011
• Species: Danio rerio
• Alignment Length: 817
• Identity: 339/818 (41%)
• Similarity: 470/818 (57%)
• Gaps: 77/818 (9%)

  Fly     9 QARILTRLLCNKMASKGLHNEDNKLDTFRRICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDT 73
            |..:|:..:|:..      ::||.|..||::|..:|.:|.|..|.|.::.|..|||.|..|:||.
Zfish   244 QGSVLSAQMCDPT------HKDNLLREFRKLCALVAEKSGYNAKTEIVRDFLTKGSGGDKFRGDL 302

  Fly    74 VLWVQFLIPAANQRVYNLQNKALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKHFAASKKLKPQ 138
            .|.|:.|:|...:.||||.:|.::||||||.|.:|..|..|||| ||||||:|..|..||...|.
Zfish   303 YLTVKLLLPGVVKNVYNLNDKQIVKLFSRILNCNQDDMVQDLEQ-GDVSETVRMFFEESKSFPPS 366

  Fly   139 KQSKLYLQEVEEMLLHLVERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDA 203
            .:|.|.:|||:..|..|.:.||||:|...||.:..|.|..||:.:||||||||:||:.|:|||||
Zfish   367 AKSLLTIQEVDASLSRLSQLTKEDDQQAELQSIAKKCTGNDLKCYIRLVKHDLKINSGAKHILDA 431

  Fly   204 FGPDAYPAYQSSRDLVAIVEQ-FATKENKNYASSPVKKTKKTSSSAIQVMTPISPMLASPCKSVE 267
            ..|:||.|:::||:|..:::: ...:::.:..:.|    :|..|....:|||:.||||..|||:|
Zfish   432 VDPNAYDAFKASRNLGDVIDRVLRNQQDASNGTGP----RKILSIEASLMTPVQPMLAEACKSIE 492

  Fly   268 DAFKKSPTGLYSEIKYDGERVQIHKQGNDFKFFSRNLKPVVDHKIRALKKYIPQAFPGGGEMILD 332
            .|.||.|.|:||||||||||||:||.||.|.:|||:||||:.||:...|.:|||||.||..||||
Zfish   493 YAMKKCPNGMYSEIKYDGERVQVHKNGNHFSYFSRSLKPVLPHKVAHFKDFIPQAFAGGHSMILD 557

  Fly   333 SEIILVDTDTGALLPFGSLGAHKKQTFANAAVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQP 397
            :|::|:||.|...||||:||.|||..|.:|.|.|||||||.::|..|...|..:||:.|..|:..
Zfish   558 AEVLLIDTKTSKPLPFGTLGVHKKAAFQDAQVGLFVFDCIYFNGVSLMDKPLCERRKFLHDNMVE 622

  Fly   398 IKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLKSPTSTYQPGKRNWLKVKKDYLFDGKMAD 462
            :.:.:..||.:.:....:||.|..||:...|||:|||.....|:||||:|||||||||.:|.|||
Zfish   623 VPNRILFSEMKHVTRAPDLAEMITRVIREGLEGLVLKDIKGLYEPGKRHWLKVKKDYLNEGAMAD 687

  Fly   463 TADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERAD 527
            |||||||||:||.|..||.:|.|||||||...|.|.||||...|.|||....:.|.|..:....|
Zfish   688 TADLVVLGAFYGKGSNGGIMSSFLMGCYDPESRKWCTVTKCSGGFDDAMLDRLQKDLDVIKIGKD 752

  Fly   528 ANAIPSWLLCSKSLVPDVLAKDPMKMPVWEITGAEFTKSDAHTASGISVRFPRITRRRSDKSAKE 592
            .:.||.||...|:..||.:.:||.|.||||||||||:||:.|||.|||:||||.||.|.||..|.
Zfish   753 PSKIPGWLKIVKNYYPDFIIRDPQKAPVWEITGAEFSKSEMHTADGISIRFPRCTRMRDDKDWKT 817

  Fly   593 ANDLAHLEDLFEASKSNVNVDLLLANCSKDETAMNNKTTPEKEKKLNGNQSNGS----------- 646
            |.:|..|::|:..||.         ||..:.||..:|.. :.:|..:|.:|.||
Zfish   818 ATNLQQLKELYRISKE---------NCDFEVTAGPSKAN-QNDKSSSGGESGGSSPSASRGASTA 872

  Fly   647 KKLKRSNT----GSDDEDGAPVL-----SKRKESKAIRSLSPSQKGLKDFFKPSKEFKSVVKKEP 702
            .|.|..:|    .:..|..||.:     :::::.|.|::.|....|       ..:.|||...:|
Zfish   873 NKPKNGHTPKAKAAKTESSAPAVKRKLPAEKQDVKKIKTESVHSNG-------QSKLKSVPTTDP 930

  Fly   703 KEDEGNIESTSSKPQLFEGLVAHFAME-KDSSKLMQQFSQHGGCCTTEPQKADLVFYANTNEALD 766
            |:::..::       :|.|:..:.... ||..||.:.|..:.|         |||  ...:.||
Zfish   931 KQEKTLLD-------IFTGVKLYLPESVKDFEKLRRYFLAYDG---------DLV--PEYDSAL- 976

  Fly   767 LEKLRTLYR----RSCRHLNVSWLQSCLDTQSRQPFP 799
              ...||.:    .|.:.:..:|:..|:  :.|:..|
Zfish   977 --ATHTLGQPEDGSSAQKVTSNWIWECI--RKRRVVP 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	79/164 (48%)
		dnl1	88..604	CDD:273147	266/517 (51%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	112/212 (53%)
		OBF_DNA_ligase_III	460..598	CDD:153436	78/138 (57%)
lig3	NP_001025345.2	zf-PARP	95..178	CDD:279039
		DNA_ligase_A_N	263..428	CDD:282522	79/166 (48%)
		dnl1	317..829	CDD:273147	266/517 (51%)
		Adenylation_DNA_ligase_III	467..679	CDD:185712	112/212 (53%)
		OBF_DNA_ligase_III	685..823	CDD:153436	78/138 (57%)
		LIG3_BRCT	935..1006	CDD:293364	19/94 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C322364423
eggNOG	1	0.900				E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H32109
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1270
OMA	1	1.010
OrthoDB	1	1.010				D189866at33208
OrthoFinder	1	1.000				FOG0007850
OrthoInspector	1	1.000				T1053343
orthoMCL	1	0.900				OOG5_134498
Panther	1	1.100			LDO	PTHR45674
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3850
TreeFam	1	0.960
ZFIN	0	0.000	Not matched by this tool.
	13	12.800