Protein Alignment: DNAlig3 and lig3

• Sequence 1: NP_650187.2
• Gene: DNAlig3
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_012827218.1
• Gene: lig3
• XenbaseID: XB-GENE-5788004
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 787
• Identity: 335/788 (43%)
• Similarity: 467/788 (59%)
• Gaps: 59/788 (7%)

  Fly    28 NEDNKLDTFRRICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDTVLWVQFLIPAANQRVYNLQ 92
            ::|..|..||::|..:|.:.||..|.:.::.|..||:||.||.|||.|.|:.|:|...:.||||.
 Frog   222 HKDCLLREFRKLCAMVAEQPSYNSKTQIIRDFLTKGTSGDGFHGDTYLTVKLLLPGVIKSVYNLN 286

  Fly    93 NKALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKHFAASKKLKPQKQSKLYLQEVEEMLLHLVE 157
            :|.::|.||||||.:|::|..|||| ||||||:|..|..||...|..:|.|.:.||:::|..|.:
 Frog   287 DKQIVKHFSRIFNCNQEEMVRDLEQ-GDVSETVRIFFEESKCFAPASKSLLTIHEVDDLLTKLSK 350

  Fly   158 RTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAFGPDAYPAYQSSRDLVAIV 222
            .|||::|.::|:.:..:.|..||:..|||:||||::|:.|:|:|||..|:||.|:::||:|..:|
 Frog   351 MTKEEDQQNVLEDIAHRCTSNDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYDAFKASRNLGDVV 415

  Fly   223 EQFATKENKNYASSPVKKTKKTSSSAIQVMTPISPMLASPCKSVEDAFKKSPTGLYSEIKYDGER 287
            |:....|.:      ....|:|.|....:|||:.||||..|||:|.|.||.|.|:|:||||||||
 Frog   416 ERVLRNEQQ------APGMKRTLSVQASLMTPVQPMLAEACKSIEYAMKKCPNGMYAEIKYDGER 474

  Fly   288 VQIHKQGNDFKFFSRNLKPVVDHKIRALKKYIPQAFPGGGEMILDSEIILVDTDTGALLPFGSLG 352
            ||:||.|:.|.:|||:||||:.||:...|.:||:|||||..||||:|::|:||:||..||||:||
 Frog   475 VQVHKNGDHFSYFSRSLKPVLPHKVAHFKDFIPKAFPGGNSMILDAEVLLIDTNTGKPLPFGTLG 539

  Fly   353 AHKKQTFANAAVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTRELA 417
            .|||..|.:|.|||||||||.::|..|...|..:||:.:..|:..|.:|:..||.:.:....:||
 Frog   540 VHKKAAFKDANVCLFVFDCIYFNGVSLMDRPLSERRKFMRDNMVEIPNHILFSEMKHVTKASDLA 604

  Fly   418 AMTARVLHANLEGVVLKSPTSTYQPGKRNWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTL 482
            .|..||:...|||:|||...|.|:||||:|||||||||.:|.|||||||.||||:||.|..||.:
 Frog   605 DMITRVIREGLEGLVLKDLKSNYEPGKRHWLKVKKDYLNEGAMADTADLAVLGAYYGKGANGGIM 669

  Fly   483 SIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPSWLLCSKSLVPDVLA 547
            |||||||||...:.|.||||..||.||||...:.|.|..:....|.:.|||||..:|:..||.:.
 Frog   670 SIFLMGCYDPESQKWCTVTKCSSGYDDATLQRLQKELNMVKISKDPSKIPSWLKINKNYFPDFII 734

  Fly   548 KDPMKMPVWEITGAEFTKSDAHTASGISVRFPRITRRRSDKSAKEANDLAHLEDLFEAS--KSNV 610
            .||.|.|:|||||||::|::||||:|:|:||||.||.|.||..|.|..|..|::|:..|  ||:.
 Frog   735 HDPKKAPIWEITGAEYSKAEAHTAAGLSIRFPRCTRFRDDKDWKTATTLQQLKELYRLSKEKSDF 799

  Fly   611 NVDLLLANCSKDETAMNNKTTPEKEKKLNGNQSNGSKKLKRSNTGSDDEDGAPVLSKRKESKAIR 675
            |:   .|..|:||...:..::.|.|.  |..|:.....:|:|........|     |.|.|::.:
 Frog   800 NI---TATSSQDEDGSSESSSRENEG--NSRQTASGSMVKKSKNAPSKSPG-----KDKTSESTK 854

  Fly   676 SLSPSQKGLKDFF-----KPSKEFKSVVKKEPKEDE---GNIESTSSKP-------QLFEGLVAH 725
             |.|.||  |:..     :.|:..|:|..|:.|..|   .|..|.:..|       .:|.|:..|
 Frog   855 -LPPPQK--KEELPKAEKRKSQTPKTVQSKKAKISETGHSNGHSIAQSPVTNKTLLDIFTGVKLH 916

  Fly   726 FAMEKDS-SKLMQQFSQHGGCCTTEPQKADLVFYANTNEALDLEKLRTLYRR------SCRHLNV 783
            .....|. :||.:.|....|         |||      ...||.....:..|      ..:|:..
 Frog   917 IPSTLDDFAKLRRYFIAFDG---------DLV------PEYDLPTATHVMGREPECIADAKHVTP 966

  Fly   784 SWLQSCL 790
            .|:..|:
 Frog   967 HWIWECI 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	74/164 (45%)
		dnl1	88..604	CDD:273147	263/516 (51%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	115/212 (54%)
		OBF_DNA_ligase_III	460..598	CDD:153436	77/138 (56%)
lig3	XP_012827218.1	zf-PARP	64..145	CDD:279039
		DNA_ligase_A_N	228..393	CDD:282522	74/166 (45%)
		dnl1	282..791	CDD:273147	263/516 (51%)
		Adenylation_DNA_ligase_III	429..641	CDD:185712	115/212 (54%)
		OBF_DNA_ligase_III	647..785	CDD:153436	77/138 (56%)
		LIG3_BRCT	905..977	CDD:293364	17/85 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C322368616
eggNOG	1	0.900				E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H32109
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D189866at33208
OrthoFinder	1	1.000				FOG0007850
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	7	6.710