Protein Alignment DNAlig3 and DNAlig1

DIOPT Version :10

• Sequence 1: NP_650187.2
• Gene: DNAlig3 / 41518
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Alignment Length: 689
• Identity: 170/689 - (24%)
• Similarity: 290/689 - (42%)
• Gaps: 139/689 - (20%)

  Fly    24 KGLHNEDNKLD-------TFRRICDEIAGESSYLKKAERLQRFFEKGS--SGKGFKGDTVLWVQF 79
            |..:.:|.|:.       || ::.:|..|.   ||..:.|..||....  |.:.......|.:..
  Fly   115 KNAYWKDKKVTPYLALARTF-QVIEETKGR---LKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQ 175

  Fly    80 LIPAANQRVYNLQNKALIKLFSRIFNAD------QQQMHLDLEQDGDVSETLRKHFAASKKLKPQ 138
            |.||.......:....|:|...:....:      |.|:..||   |.|:|..|    .|:::..|
  Fly   176 LAPAYEGLELGVAETTLMKAICKATGRNLAHIKSQTQLTGDL---GIVAEQSR----VSQRMMFQ 233

  Fly   139 KQSKLYLQEVEEMLLHLVERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDA 203
             .:.|.:::|...|..:.:.:.:.:. ||:..:.......:.|.|||.:...|||....:.:|.|
  Fly   234 -PAPLNVRDVFRKLREIAKLSGQSKM-DLVYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTA 296

  Fly   204 FG-----------------PDAY------------------PAYQSSRDLVAIVEQFATKENKNY 233
            ..                 ||.|                  |.|..   ::..:.::..||.:
  Fly   297 LAIGLVKKNHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDI---IIPAILKYDIKELQ-- 356

  Fly   234 ASSPVKKTKKTSSSAIQVMTPISPMLASPCKSVEDAFKK-SPTGLYSEIKYDGERVQIHK-QGND 296
                       ....:....|:.||||.|.|.|.:.|:: ....:..|.||||||.|||: :..:
  Fly   357 -----------ERCPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGERAQIHRNEKGE 410

  Fly   297 FKFFSRNLK------PVVDHKIRALKKYIPQAFPGGGEMILDSEIILVDTDTGALLPFGSLGAHK 355
            ...||||.:      |.:..:..||.|...:::      |:||||:..|.:...:|||..|...|
  Fly   411 ISIFSRNSENNTAKYPDLIARSTALLKGDVKSY------IIDSEIVAWDVERKQILPFQVLSTRK 469

  Fly   356 KQTF----ANAAVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTREL 416
            ::..    ....||:::||.:..:|..|......:||::|.::.|.::...:.:.:.......|:
  Fly   470 RKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEV 534

  Fly   417 AAMTARVLHANLEGVVLKS--PTSTYQPGK--RNWLKVKKDYLFDGKMADTADLVVLGAWYGSGK 477
            .......:..|.||:::|:  ..:||:..|  |||||:|||||  ..:.|:.||||:|.:.|.|:
  Fly   535 QQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYL--SNVGDSLDLVVIGGYKGKGR 597

  Fly   478 KGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPSWLLCSKSLV 542
            :.||...||:.|||.....::::.|:.:|..| .:.:.|...:   .:...:|..|:.....||.
  Fly   598 RTGTYGGFLLACYDTENEEYQSICKIGTGFTD-EDLQTHSEFL---GKHVTSAAKSYYRYDPSLE 658

  Fly   543 PDVLAKDPMKMPVWEITGAEFTKSDAHTAS--------GISVRFPRITRRRSDK---SAKEANDL 596
            ||... :|::  |||:..|:.:.|..|.|:        |||:||||..|.|.||   :|.:||.:
  Fly   659 PDHWF-EPVQ--VWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQV 720

  Fly   597 AHLEDLFEASKSNVNVDLLLANCSKDETAMNNKTTPEKE 635
            ||:..                  |:|:...|.|::.:.|
  Fly   721 AHMYQ------------------SQDQVKNNQKSSTQME 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	dnl1	88..604	CDD:273147	148/583 (25%)
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	170/689 (25%)