Protein Alignment: DNAlig3 and Lig4

• Sequence 1: NP_650187.2
• Gene: DNAlig3
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_795927.2
• Gene: Lig4
• MGIID: 1335098
• Length: 911
• Species: Mus musculus
• Alignment Length: 857
• Identity: 195/858 (23%)
• Similarity: 327/858 (38%)
• Gaps: 218/858 (25%)

  Fly    36 FRRICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDTVLWVQF--------------------- 79
            |..:|..:          ||:|:..::....:.||.....|.:|
Mouse    16 FADLCSTL----------ERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDVTDSFYPAMRL 70

  Fly    80 LIPAANQR--VYNLQNKALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKH------------FA 130
            ::|...:.  .|.::...|.||:..:.|         |.::|..::.|..:            ||
Mouse    71 ILPQLERERMAYGIKETMLAKLYIELLN---------LPREGKDAQKLLNYRTPSGARTDAGDFA 126

  Fly   131 --ASKKLKPQ--KQSKLYLQEVEEMLLHLVERTKEDEQTDLLQK----LCSKATDLDLRTFIRLV 187
              |...|||:  ::..|.:|:|.| ||.||......::.||::|    |.::::.|:.:..||::
Mouse   127 MIAYFVLKPRCLQKGSLTIQQVNE-LLDLVASNNSGKKKDLVKKSLLQLITQSSALEQKWLIRMI 190

  Fly   188 KHDLRINARARHILDAFGPDAYPAYQSSRDLVAIVEQFATKENKNYASSPVKKTKKTSSSAIQVM 252
            ..||::....:.|...|..||...:..:.||..:..|.         ..|   :...|..:|.:.
Mouse   191 IKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQL---------HDP---SVGLSDISITLF 243

  Fly   253 TPISPMLA--SPCKSVEDAFKKSPTGLYSEIKYDGERVQIHKQGNDFKFFSRNLKPVVDH----- 310
            :...||||  :..:.||...|:.  ..|.|.|.||||:|:||.|..:::||||.....|.
Mouse   244 SAFKPMLAAVADVERVEKDMKQQ--SFYIETKLDGERMQMHKDGALYRYFSRNGYNYTDQFGESP 306

  Fly   311 KIRALKKYIPQAFPGGGEM---ILDSEIILVDTDTGALLPFGSLGAHKKQTFANAAV-------- 364
            :..:|..:|..||  |.::   |||.|::..:..|              |||....|
Mouse   307 QEGSLTPFIHNAF--GTDVQACILDGEMMAYNPTT--------------QTFMQKGVKFDIKRMV 355

  Fly   365 -------CLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTRELAAMTAR 422
                   |..|||.::.:.:.|.:...|||.|||.....||:..:::.:.....|.:|:......
Mouse   356 EDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALND 420

  Fly   423 VLHANLEGVVLKSPTSTYQPGKR--NWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTLSIF 485
            .:....||:::|.|.|.|:|.||  .|||:|.:|: .|.| |..|::::|.::|.|.:||.:|.|
Mouse   421 AIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYV-SGLM-DELDVLIVGGYWGKGSRGGMMSHF 483

  Fly   486 LMGCYDA-----FGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPSWLLCSKSLVPDV 545
            |....:.     ...::.|:.:|.||.......::...|.|..:.....:.||.:||... .|:|
Mouse   484 LCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTE-KPEV 547

  Fly   546 LAKDPMKMPVWEITGAEFTKSDAHTASGISVRFPRITRRRSDKSAKEANDLAHLEDLFEASKSNV 610
            .. :|....:.:|..||...||.: .:|.::|||||.:.|.||...|...|..||.|
Mouse   548 YI-EPQNSVIVQIKAAEIVPSDMY-KTGSTLRFPRIEKIRDDKEWHECMTLGDLEQL-------- 602

  Fly   611 NVDLLLANCSKDETAMNNKTTPEKEKKLNGNQSNGSKKLKRSNTGSDDEDGAPVLSKRKESKAIR 675
                                         ..:::|....|..:.|.|||
Mouse   603 -----------------------------RGKASGKLATKHLHVGDDDE---------------- 622

  Fly   676 SLSPSQKGLKDFFKPSKEFKSVVK-KEPKEDEGNIESTSSKPQLFE--------GLVAHFAMEKD 731
               |.:|..|...|..|..:.:.. |.|     |:.:.:....:||        ||..:     .
Mouse   623 ---PREKRRKPISKTKKAIRIIEHLKAP-----NLSNVNKVSNVFEDVEFCVMSGLDGY-----P 674

  Fly   732 SSKLMQQFSQHGGCCTTEPQKADLVFYANTNEALDLEKLRTLYRRSCRHLNV---SWLQSCLDTQ 793
            .:.|..:.::.||.....|........|.:      |.:|.....|....:|   .||..|..|:
Mouse   675 KADLENRIAEFGGYIVQNPGPDTYCVIAGS------ENVRVKNIISSDKNDVVKPEWLLECFKTK 733

  Fly   794 SRQP----FPLH 801
            :..|    |.:|
Mouse   734 TCVPWQPRFMIH 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	41/207 (20%)
		dnl1	88..604	CDD:273147	151/568 (27%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	67/239 (28%)
		OBF_DNA_ligase_III	460..598	CDD:153436	40/143 (28%)
Lig4	NP_795927.2	DNA_ligase_A_N	15..203	CDD:282522	41/207 (20%)
		dnl1	81..602	CDD:273147	150/566 (27%)
		Adenylation_DNA_ligase_IV	235..455	CDD:185713	68/238 (29%)
		OBF_DNA_ligase_IV	459..596	CDD:153437	39/141 (28%)
		BRCT	656..730	CDD:214602	16/85 (19%)
		DNA_ligase_IV	750..782	CDD:288294
		BRCT	830..899	CDD:237994

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910