Protein Alignment: DNAlig3 and Lig3

• Sequence 1: NP_650187.2
• Gene: DNAlig3
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_006247051.1
• Gene: Lig3
• RGDID: 1309875
• Length: 1002
• Species: Rattus norvegicus
• Alignment Length: 790
• Identity: 337/791 (43%)
• Similarity: 460/791 (58%)
• Gaps: 58/791 (7%)

  Fly    14 TRLLCNKMASKGLHNEDNKLDTFRRICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDTVLWVQ 78
            |.|..:|...|   ::|..|..||::|..:|...||..|.:.:..|.:|||:|.||:||..|.|:
  Rat   249 TSLSASKCDPK---HKDCLLREFRKLCAMVAENPSYNTKTQIIHDFLQKGSTGDGFRGDVYLTVK 310

  Fly    79 FLIPAANQRVYNLQNKALIKLFSRIFNADQQQMHLDLEQDGDVSETLRKHFAASKKLKPQKQSKL 143
            .|:|...:.||||.:|.::||||||||.:...|..|||| ||||||:|..|..||...|..:|.|
  Rat   311 LLLPGVIKSVYNLNDKQIVKLFSRIFNCNPDDMARDLEQ-GDVSETIRVFFEQSKSFPPAAKSLL 374

  Fly   144 YLQEVEEMLLHLVERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAFGPDA 208
            .:|||:..||||.:.||||||...||.:.|:.|..||:..|||:||||::|:.|:|:|||..|:|
  Rat   375 TIQEVDAFLLHLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNA 439

  Fly   209 YPAYQSSRDLVAIVEQFATKENKNYASSPVKK---TKKTSSSAIQVMTPISPMLASPCKSVEDAF 270
            |.|:::||:|..:||:....|.:      |:|   .::..|....:|||:.||||..|||:|.|.
  Rat   440 YEAFKASRNLQDVVERVLHNEQE------VEKDPGRRRALSVQASLMTPVQPMLAEACKSIEYAM 498

  Fly   271 KKSPTGLYSEIKYDGERVQIHKQGNDFKFFSRNLKPVVDHKIRALKKYIPQAFPGGGEMILDSEI 335
            ||.|.|::|||||||||||:||:|:.|.:|||:||||:.||:...|.|||:|||||..||||||:
  Rat   499 KKCPNGMFSEIKYDGERVQVHKKGDHFSYFSRSLKPVLPHKVAHFKDYIPKAFPGGQSMILDSEV 563

  Fly   336 ILVDTDTGALLPFGSLGAHKKQTFANAAVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKS 400
            :|:|.:||..||||:||.|||..|.:|.|||||||||.::...|...|..:||:.|..|:..|::
  Rat   564 LLIDNNTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRN 628

  Fly   401 HVQLSESEFLKTTRELAAMTARVLHANLEGVVLKSPTSTYQPGKRNWLKVKKDYLFDGKMADTAD 465
            .:..||.:.:....:||.|..||:...|||:|||....||:||||:|||||||||.:|.||||||
  Rat   629 RIMFSEMKQVTKASDLADMINRVIREGLEGLVLKDVKGTYEPGKRHWLKVKKDYLNEGAMADTAD 693

  Fly   466 LVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERADANA 530
            ||||||:||.|.|||.:|||||||||...:.|.||||...|.||||.|.:.|.|..:....|.:.
  Rat   694 LVVLGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLARLQKELDMVKISKDPSK 758

  Fly   531 IPSWLLCSKSLVPDVLAKDPMKMPVWEITGAEFTKSDAHTASGISVRFPRITRRRSDKSAKEAND 595
            |||||..:|...||.:..||.|..|||||||||::|:||||.|||:||||.||.|.||..|.|.:
  Rat   759 IPSWLKINKIYYPDFIVPDPKKAAVWEITGAEFSRSEAHTADGISIRFPRCTRIRDDKDWKSATN 823

  Fly   596 LAHLEDLFEASKSNVNVDLLLANCSKDETAMNN--------KTTPEKEKKLNGNQSNGSKKLKRS 652
            |..|::|::.||...:..::..:.....|..:|        .|.|.|..|  |..|..|...|::
  Rat   824 LPQLKELYQLSKDKADFAVVAGDEGSSTTGGSNGENEGTAGSTVPRKGPK--GPPSKSSASAKKT 886

  Fly   653 NTGSDDEDGAPVLSKRKESKAIRSLSPSQKGLKDFFKPSKEFKSVVKKEPKEDEGNIESTSSKPQ 717
            ....:|..     |:..|..|::| ||.:.|:|             :|...|..|   .|.:...
  Rat   887 EQKLNDPS-----SRGGEKLAVKS-SPVKVGMK-------------RKAADETPG---LTKALLD 929

  Fly   718 LFEGLVAHF-AMEKDSSKLMQQFSQHGGCCTTEPQKADLV-FYANTNEALDLEKLRTLYRRSCRH 780
            :|.|:..:. ....|..:|.:.|....|....|...|... ...|.::..|.:.:.:
  Rat   930 VFTGVRLYLPPSTPDFRRLKRYFVAFNGDLVQEFDMASATHVLGNRDKNTDAQLVSS-------- 986

  Fly   781 LNVSWLQSCL 790
               .|:.:|:
  Rat   987 ---EWIWACI 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	80/164 (49%)
		dnl1	88..604	CDD:273147	274/519 (53%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	113/212 (53%)
		OBF_DNA_ligase_III	460..598	CDD:153436	81/138 (59%)
Lig3	XP_006247051.1	zf-PARP	98..178	CDD:279039
		DNA_ligase_A_N	266..431	CDD:282522	80/166 (48%)
		dnl1	320..832	CDD:273147	274/519 (53%)
		Adenylation_DNA_ligase_III	470..682	CDD:185712	113/212 (53%)
		OBF_DNA_ligase_III	688..826	CDD:153436	81/138 (59%)
		LIG3_BRCT	927..997	CDD:293364	12/79 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C322365477
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H32109
Inparanoid	1	1.050	589	1.000	Inparanoid score	I941
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D189866at33208
OrthoFinder	1	1.000				FOG0007850
OrthoInspector	1	1.000				T1087706
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR45674
Phylome	1	0.910		0.667	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	8	8.000