DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and AgaP_AGAP004160

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	XP_562672.3	Gene:	AgaP_AGAP004160 / 3290969	VectorBaseID:	AGAP004160	Length:	331	Species:	Anopheles gambiae

Alignment Length:	304	Identity:	128/304 - (42%)
Similarity:	167/304 - (54%)	Gaps:	29/304 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 SRVNKSGIFDSNQLLLAKHALGGVVIGGSRVLQCRYEFEAQAPERVQIRFHDFNVPTEHENSTGC 447
            |....||:|.|:...|                   |||.....|||||.|.:|.:|:. ...|.|
Mosquito    27 SHSKHSGLFPSSLCQL-------------------YEFVGDGAERVQIIFSEFRLPST-LGPTEC 71

  Fly   448 QPGDALHVVTELRGRYETQELLCGAFLPKPLMSSGQQLHLQFVGKYPPTMTNKVQYYGFRAEYRF 512
            ...|.|.|...:.||.|..|.|||..||||::|.|.:|.|:....|     |..:..||..::.|
Mosquito    72 GDTDILMVYYIVNGREELVETLCGDTLPKPILSDGSRLLLELRSSY-----NNTENKGFTGDFFF 131

  Fly   513 LTNFGIMSGIQ--KEGCSFVYNSSERISGLFHSPNFPGYYLENVVCNYYFYGASDERVVLHFTYF 575
            ||||||.:|.|  :..|:|.|..:....|...||||||.|..|::|||.|:|..::.|.:.||||
Mosquito   132 LTNFGIPNGFQPNQSECTFHYFRNVTSQGWIQSPNFPGAYPRNIICNYLFHGGPNDFVHVRFTYF 196

  Fly   576 DIEGIGSCDHQTASDYIEFSNFMSTDRKFSRYCGKLPDFEMRSDGRFFRVTLHSNDRFVAIGFRA 640
            |||||..||..|||||:|||||::.|||::.|||...:..:||||||||:|:.||||....||||
Mosquito   197 DIEGIRPCDEDTASDYVEFSNFVTRDRKYAMYCGSWRELVVRSDGRFFRITMVSNDRLDGTGFRA 261

  Fly   641 LYTFETVSVNNSITDLRDNASMQSFVSTASTQPVANVNKLIACI 684
            |||||||.|..  |:..:.|||....:|::...:.....|:|.|
Mosquito   262 LYTFETVPVET--TERTEVASMGKVTTTSAASRLHGSLSLMALI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001
		CUB	<414..512	CDD:238001	35/97 (36%)
		CUB	527..644	CDD:238001	64/116 (55%)
AgaP_AGAP004160	XP_562672.3	CUB	9..131	CDD:294042	41/128 (32%)
AgaP_AGAP004160	XP_562672.3	CUB	155..265	CDD:238001	61/109 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I9927
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122064
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0017010
OrthoInspector	1	1.000	-	-		oto107347
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4379
TreeFam	0	0.000	Not matched by this tool.
	6	5.910