Protein Alignment GstD1 and AIMP2

DIOPT Version :10

• Sequence 1: NP_524326.1
• Gene: GstD1 / 41503
• FlyBaseID: FBgn0001149
• Length: 209
• Species: Drosophila melanogaster
• Sequence 2: NP_006294.2
• Gene: AIMP2 / 7965
• HGNCID: 20609
• Length: 320
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 45/212 - (21%)
• Similarity: 81/212 - (38%)
• Gaps: 53/212 - (25%)

  Fly    14 RSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHT---IPTLVDN---------------- 59
            :.:::.|......|:..:|:....||    |..::..||   :.::.:|
Human   120 KDIVINANPASPPLSLLVLHRLLCEH----FRVLSTVHTHSSVKSVPENLLKCFGEQNKKQPRQD 180

  Fly    60 ---GFAL-WESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDM---------GTLYQSFAN 111
               ||.| |::       |.|.....|:...||.:......|..|.:         .||..|:.:
Human   181 YQLGFTLIWKN-------VPKTQMKFSIQTMCPIEGEGNIARFLFSLFGQKHNAVNATLIDSWVD 238

  Fly   112 YYYPQVFAKAPADPEAFKKIEAA-FEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEVAKFEIS 175
            ....|:       .|...|.:|| |..:|:.|....:.||:.|||||:.|.:.:.  ::....::
Human   239 IAIFQL-------KEGSSKEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVLQ--QIGGCSVT 294

  Fly   176 KYANVNRWYENAKKVTP 192
            ..|||.||..:.:.:.|
Human   295 VPANVQRWMRSCENLAP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD1	NP_524326.1	GST_N_Delta_Epsilon	2..75	CDD:239343	13/83 (16%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	27/114 (24%)
AIMP2	NP_006294.2	AIMP2_LysRS_bd	1..44	CDD:465269
		Interaction with PRKN. /evidence=ECO:0000269|PubMed:16135753	82..162		8/45 (18%)
		Thioredoxin_16	117..208	CDD:436585	18/98 (18%)
		Interaction with TP53. /evidence=ECO:0000269|PubMed:18695251	162..225		12/69 (17%)
		GST_C_AIMP2	214..309	CDD:198309	26/103 (25%)