Protein Alignment Su(var)3-9 and ehmt1b

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_021324462.1
• Gene: ehmt1b / 402830
• ZFINID: ZDB-GENE-080515-3
• Length: 1295
• Species: Danio rerio
• Alignment Length: 848
• Identity: 185/848 - (21%)
• Similarity: 297/848 - (35%)
• Gaps: 280/848 - (33%)

  Fly     1 MATAEAQIGVNRNLQKQDLSNLDVSKL-----------TPLSPEVISRQATINIGTIGHVAHGKS 54
            :|..||.:..........|.:.|...:           ||.|.|:::            :|..|.
Zfish   476 LAAQEALLTSQNTAASGSLQSTDADMVQELPLCSCRMETPKSREILT------------LADRKC 528

  Fly    55 TVVKAISG----VQTVRFKNELERNITIKLERLSEKKIKNLLTSKQQRQQYEIKQRSMLRHLA-- 113
            ...::|.|    .|:...|:|:.|         ....::.|:..:..|       ..|::|..
Zfish   529 MATESIDGQLSRCQSAVLKHEMMR---------PSNSVQLLVLCEDHR-------TGMVKHQCCP 577

  Fly   114 ----------------ELRRHSRFRRLCT-------------KPASSSMPASTSSVDRRTTRRST 149
                            |:....||.|.|.             :..|.:...:.:..|..:|...|
Zfish   578 GCGFFCRAGTFMECQPEVNISHRFHRTCASVLNGQSFCPHCGEEVSKAKEVTIAKADTTSTVPIT 642

  Fly   150 SQTSLSPSNSSGYG----------SVFG-----------CEEHDVDKIPSLNGFAKLKRRRSSCV 193
             .:|..||.|.|..          ||.|           .|..|...  ||.|........::..
Zfish   643 -HSSCIPSTSEGKADTTTGGSTRLSVLGEGKANSTLPKPSESQDTSL--SLVGSKARSVAMAAAP 704

  Fly   194 GAPTPNSKRSKNNMGVI----AKRP------PKGEYV------VERIECVEMDQYQPVFFVKWLG 242
            |.|.|.....:....|:    |::|      ||..|:      ::::..:.:|...|.|.:
Zfish   705 GLPLPPGPPKETLQSVLLALDAEKPKKLRFHPKQLYISAKQGELQKVLLMLVDGIDPNFKM---- 765

  Fly   243 YHDSENTWESL-------------------ANVADCAE------MEKFVERHQQ----------- 271
              :|:|....|                   ||:..|.|      ||.....|.:
Zfish   766 --ESQNKRTPLHVAAEAGHQDVCHMLVQAGANLDMCDEDQRTPLMEACENNHLETVRYLLRAGAI 828

  Fly   272 -------------------------------LYEI-------YIAKITTELEKQLEALPLM---- 294
                                           |.:|       :.|.|.....|.::.:.|:
Zfish   829 VSHKDVEGSTCLHLAAKNGHFSIVQHLLSAGLVDINCQDDGGWTAMIWATEYKHVDQVKLLLSKG 893

  Fly   295 ---------ENI-----------TVAE-------------VDAYEPLNL-----QIDLILLAQYR 321
                     |||           .:||             :....||::     ::|.:.|...|
Zfish   894 ADINIRDKEENICLHWAAFSGCVEIAEIFLTAKCDLNTMNIHGDSPLHIASREGRLDCVNLFLSR 958

  Fly   322 AAG----SRSQREPQKIGERALKSMQIKRAQFVRRKQLADLALFEKRMNH-----VEKPSPPIRV 377
            .|.    ::....|.:....:.|.....:|...:|:........||.:|.     .||  .|:..
Zfish   959 GADVNLKNKEGETPMECCSHSSKVWNALQANKKQREANRKAGATEKLLNKDIARGYEK--VPVPC 1021

  Fly   378 ENNIDLDTIDSNFMYIHDNIIGK--DVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELFAYER 440
            .|.:|.:....|:.|:.|:.:..  ::.|....:..|.|.:|   |::::..|.:.:...: |::
Zfish  1022 VNAVDSEPCPDNYKYVPDSCVTSPLNIDKNITHLQYCVCKDD---CSSASCMCGQLSLRCW-YDK 1082

  Fly   441 STRRL----RLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAATALRKG 501
            .:|.|    ...| ..|:|||..|||..:|.||:||:|.:..|.|||| ...||||:....:.:|
Zfish  1083 ESRLLPEFSNEEP-PLIFECNHACSCWRTCKNRVVQNGLRTRLQLFKT-QMMGWGVKTLQDIPQG 1145

  Fly   502 EFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPN 566
            .|||||:||||:..||:.|      ...:|||.||....  ..|.:||..|||||.||||.|:||
Zfish  1146 TFVCEYVGEIISDAEADVR------ENDSYLFSLDSKVG--DMYCVDARFYGNISRFINHHCEPN 1202

  Fly   567 LAVFPC--WIEHLNVALPHLVFFTLRPIKAGEELSFDYIRADN-EDVPYENLSTAVRVECRCGAD 628
            |  .||  :..|.::..||:.||..:.|.||:||.|||  .|: .||..:..:      |:||:.
Zfish  1203 L--LPCRVFTSHQDLRFPHIAFFACKNISAGDELGFDY--GDHFWDVKGKLFN------CKCGSS 1257

  Fly   629 NCR 631
            .|:
Zfish  1258 KCK 1260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	14/83 (17%)
		Chromo	219..268	CDD:459793	13/79 (16%)
		SET_SUV39H	388..634	CDD:380940	91/253 (36%)
ehmt1b	XP_021324462.1	EHMT_ZBD	503..632	CDD:411018	22/156 (14%)
		ANKYR	720..973	CDD:440430	36/258 (14%)
		ANK repeat	739..765	CDD:293786	4/25 (16%)
		ANK repeat	767..800	CDD:293786	5/32 (16%)
		ANK repeat	802..833	CDD:293786	3/30 (10%)
		ANK repeat	835..867	CDD:293786	2/31 (6%)
		ANK repeat	869..900	CDD:293786	4/30 (13%)
		ANK repeat	902..933	CDD:293786	5/30 (17%)
		ANK repeat	935..966	CDD:293786	6/30 (20%)
		SET	1033..1262	CDD:394802	91/252 (36%)