Protein Alignment Su(var)3-9 and set-32

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_492529.2
• Gene: set-32 / 183391
• WormBaseID: WBGene00008062
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 108/498 - (21%)
• Similarity: 184/498 - (36%)
• Gaps: 146/498 - (29%)

  Fly   239 KWLGYHDSEN-TWESLANVADCAEMEKFVERHQQLYEIYIA----KITTELEKQ---LEALPLME 295
            |.|..|.|.. ..|.||:.....|...|  :.:|.:.||:|    :..|.|::.   :|..|.:|
 Worm    11 KKLRQHSSRGPITEMLASNMCIFEAPPF--KAEQDFPIYLAAGYEERRTFLKESACLVETKPDVE 73

  Fly   296 NITVAEVDAYEPL----NLQIDLILLAQYRAAGSRSQREPQK------IGERALKSMQIKRAQFV 350
            |.:.:.|.....:    :|..:..||.:|        .|..|      :|:||:.|..
 Worm    74 NYSQSHVKVLNKIRNDPHLNGNWKLLPKY--------DEDVKGTMMRILGQRAMISQG------- 123

  Fly   351 RRKQLA-------DLALFEKRMNHVEKPSPPIRVENNIDLDTID-----SN-------------- 389
            |..:::       |:.|...  .:: .|...|||..|:..:|:|     |:
 Worm   124 REHEISTCPDSGQDVPLLSP--TYI-TPRKRIRVTENLTFNTLDIVPVYSDLPDEKLTSIQIPDT 185

  Fly   390 --FMYIHDNII----GKDVPK------PEAGIVGCKCTEDTE--ECTASTKC-C----------- 428
              |.|...|::    .:::.|      .|...:.|.|.....  .|..:..| |
 Worm   186 LLFEYTDTNVLNPCSARNIAKACIMSQKEENTIRCDCCSSNPIVPCYENENCPCYKLNQKLQGLQ 250

  Fly   429 -----------ARFAGELFAYERST--RRLRLRPGSAIYECNSRCSCDSSCSNR--LVQHGRQVP 478
                       |.|...:|:...||  |.:.       :.|:..|.|..:|:|.  |:.:.:..|
 Worm   251 INSSSHPPTKFASFDPVMFSNSNSTFDRCIG-------FSCSEACGCKGNCTNNSLLILNKKLFP 308

  Fly   479 LVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAY------------------- 524
            |.::::....|:|:|::..:..|..|.|:.|||:..::.:...:.|
 Worm   309 LEIYRSNENVGFGLRSSVLIPAGTAVLEFTGEIVERNQLDRDSQDYAYQLTDKDNSNWRRLLDTM 373

  Fly   525 --DDNGRTYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFF 587
              .|:.:.:|..|.|     .|:.||....||:...|.|||.|||.:...:.:.|:.|..||||.
 Worm   374 KFSDDYKKFLKKLSY-----EEFFIDPKAKGNVGRMICHSCSPNLEIVRVYQKGLSPAHVHLVFI 433

  Fly   588 TLRPIKAGEELSFDYIRADNEDVPYENLSTAVRVECRCGADNC 630
            :|..|..|..|:.||        .|..:...:..:|.||:..|
 Worm   434 SLLNIYPGTPLTMDY--------GYNYMKNHLNGKCECGSFAC 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362
		Chromo	219..268	CDD:459793	9/29 (31%)
		SET_SUV39H	388..634	CDD:380940	68/319 (21%)
set-32	NP_492529.2	SET	307..455	CDD:214614	41/160 (26%)