Protein Alignment Su(var)3-9 and met-1

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_491340.2
• Gene: met-1 / 172026
• WormBaseID: WBGene00016603
• Length: 1604
• Species: Caenorhabditis elegans
• Alignment Length: 656
• Identity: 145/656 - (22%)
• Similarity: 229/656 - (34%)
• Gaps: 192/656 - (29%)

  Fly    17 QDLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLE 81
            |..:|..||.|.|..||....:..:..|       |.:|            ||
 Worm   318 QSFTNDSVSPLPPPPPEPAPAREKVENG-------GPTT------------FK------------ 351

  Fly    82 RLSEKKIKNLLTSKQQRQQYEIKQRSMLRHLAELRRHSRFRRLCTKPASSSMPASTSSVDRRTTR 146
             ::.||..|:                      .:.:.|.|.:..:.|.|||:   :||:......
 Worm   352 -MTFKKAANI----------------------PILKTSAFEQPSSPPPSSSV---SSSISLSEVN 390

  Fly   147 RSTSQTS-LSPSNSSGYGSVFGCEE---HDVDKIPSLNGFAKLKRRRSS-----------CVGAP 196
            .|||..| .||:..|....:....|   ..:.::|.|:.|......||:           .:...
 Worm   391 SSTSIASESSPAKRSSNFDLTASNELPPPQMVELPKLSFFNMPPAVRSAEDDSAMTSEEPILLLR 455

  Fly   197 TPNSKRSKNNMGVIAKRPP----------------KGEYVVERIECVEMDQYQPVFFVKWLGYHD 245
            :|||....::...:...||                |...|:.|.|..|.|          :.:.:
 Worm   456 SPNSATPDDDALFLTTPPPPKMTESEIQALKVATEKVNQVIARREDSEKD----------VRHRE 510

  Fly   246 SENTWESLANVADCAEMEKFVERHQQLYEIYIAKITTELEKQLEALPLMENITVAEVDAYEPLNL 310
            ..:.::...:..|....:...||:.|       :.....:.:..|......:|.......|.:.|
 Worm   511 DRDDYDRRRDDRDRRSRKTDSERNDQ-------RGRQREDDERRAREREREVTKRHDREREEMRL 568

  Fly   311 QIDLILLAQYRAAGSRSQREPQKIGERALKSMQIK-RAQFVRRKQLADLALFEKRMNHVEKPSPP 374
            |                   .||..||..|..:.: :.:...:||..|.|..|:....:::.
 Worm   569 Q-------------------KQKDEERRKKDEEERIQKENDEKKQKEDEAKMEEEKKKIKEE--- 611

  Fly   375 IRVENNIDLDTIDSNFMYIHDNIIGKDVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELFAYE 439
               |..|....:.|...|:..|...|   |.|:  :.|:|......|:.:| |..|
 Worm   612 ---EMKIPEFELISESKYLTRNANKK---KTES--LTCECHRTGGNCSDNT-CVNR--------- 658

  Fly   440 RSTRRLRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFV 504
                       :.:.||.|  ||...|.|:.....:...:..|.|....|.|:||...::||.|:
 Worm   659 -----------AMLTECPS--SCQVKCKNQRFAKKKYAAVEAFHTGTAKGCGLRAVKDIKKGRFI 710

  Fly   505 CEYIGEIITSDEANERGKAY---DDNGRTYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPN 566
            .|||||::..|:..:|...|   ..:...||.|       ...|||||..|||.|.|:|||||||
 Worm   711 IEYIGEVVERDDYEKRKTKYAADKKHKHHYLCD-------TGVYTIDATVYGNPSRFVNHSCDPN 768

  Fly   567 LAVFPCWIEHLNVALP-------HLVFFTLRPIKAGEELSFDYIRADNEDVPYENLSTAVRVECR 624
             |:...|      ::|       .:.||:.|.||||||::|||        .:.|.....: :|.
 Worm   769 -AICEKW------SVPRTPGDVNRVGFFSKRFIKAGEEITFDY--------QFVNYGRDAQ-QCF 817

  Fly   625 CGADNC 630
            ||:.:|
 Worm   818 CGSASC 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362	13/62 (21%)
		Chromo	219..268	CDD:459793	6/48 (13%)
		SET_SUV39H	388..634	CDD:380940	76/253 (30%)
met-1	NP_491340.2	PRK12323	<23..263	CDD:481241
		AWS	637..682	CDD:197795	14/69 (20%)
		SET	682..828	CDD:394802	57/165 (35%)
		WW	1366..1393	CDD:238122