Protein Alignment Su(var)3-9 and Kmt2b

DIOPT Version :10

• Sequence 1: NP_524357.2
• Gene: Su(var)3-9 / 41483
• FlyBaseID: FBgn0263755
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001414070.1
• Gene: Kmt2b / 102550344
• RGDID: 7678027
• Length: 2714
• Species: Rattus norvegicus
• Alignment Length: 274
• Identity: 81/274 - (29%)
• Similarity: 115/274 - (41%)
• Gaps: 73/274 - (26%)

  Fly   373 PPI------RVENNIDLDTIDS-NFMYIHDNIIGKDVPKPEAGIVGCKCTEDTEECTASTKCCAR 430
            ||:      |.|..:...|.|. ||:.....::      ||    |..|.|:.:|...
  Rat  2501 PPLNPHGAARAEVYLRKCTFDMFNFLASQHRVL------PE----GATCDEEEDEVQL------- 2548

  Fly   431 FAGELFAYERSTRR---LRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGV 492
                     |||||   |.| |.:..:....:.|.::....|...|||               |:
  Rat  2549 ---------RSTRRATSLEL-PMAMRFRHLKKTSKEAVGVYRSAIHGR---------------GL 2588

  Fly   493 RAATALRKGEFVCEYIGEIITSDEANERGKAYDDNG-RTYLFDLDYNTAQDSEYTIDAANYGNIS 556
            .....:..||.|.||.|.:|.|...::|.|.||..| ..|:|.:|     |.: .:||..:||.:
  Rat  2589 FCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMD-----DFD-VVDATMHGNAA 2647

  Fly   557 HFINHSCDPNLAVFPCWIEHLNV-ALPHLVFFTLRPIKAGEELSFDYIRADNEDVPYENLSTAVR 620
            .||||||:||     |:...::| ...|:|.|.||.|..||||::||      ..|.|:.|.  :
  Rat  2648 RFINHSCEPN-----CFSRVIHVEGQKHIVIFALRRILRGEELTYDY------KFPIEDASN--K 2699

  Fly   621 VECRCGADNCRKVL 634
            :.|.|||..||:.|
  Rat  2700 LPCNCGAKRCRRFL 2713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-9	NP_524357.2	PTZ00327	11..>80	CDD:240362
		Chromo	219..268	CDD:459793
		SET_SUV39H	388..634	CDD:380940	74/251 (29%)
Kmt2b	NP_001414070.1	zf-CXXC	956..1003	CDD:366873
		PHD1_KMT2B	1202..1248	CDD:277064
		PHD2_KMT2B	1250..1299	CDD:277066
		PHD3_KMT2B	1336..1392	CDD:277068
		Bromo_ALL-1	1373..1515	CDD:99925
		ePHD_KMT2B	1580..1684	CDD:277164
		FYRN	1732..1779	CDD:461787
		PHA03247	<1807..2315	CDD:223021
		FYRC	2412..2496	CDD:197781
		SET_KMT2A_2B	2561..2714	CDD:380947	59/187 (32%)