Protein Alignment Cog1 and Cog1

DIOPT Version :10

• Sequence 1: NP_650162.1
• Gene: Cog1 / 41479
• FlyBaseID: FBgn0037998
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_551520.4
• Gene: Cog1 / 3290456
• VectorBaseID: AGAMI1_000876
• Length: 931
• Species: Anopheles gambiae
• Alignment Length: 946
• Identity: 311/946 - (32%)
• Similarity: 509/946 - (53%)
• Gaps: 83/946 - (8%)

  Fly     4 NLLNLNVDTLFEQHSVSEIDEVHKKIQSVVENKREELRTHVGERYRDLLQAADTIAAMQTSAGTL 68
            :|||::||.||:||:|:|||.|||::.:.:|.|||||||.|||||||||:|||||..|:.:||::
Mosquito     6 DLLNIDVDQLFKQHNVAEIDLVHKRVLNEIELKREELRTMVGERYRDLLKAADTIGDMKQTAGSI 70

  Fly    69 MEQVRHVQANCRSLNEQQLLGFQSTANASAKDAALKERNAGKKLQTYYGTMAQIKLLTALPELIW 133
            :..|..:.|.|:.||:..|:||::..:........::.|       ::|.:.||||||:|||:||
Mosquito    71 IGNVDRITARCQQLNDHNLIGFRTGTDYQRMQKKHRDHN-------FHGVIVQIKLLTSLPEMIW 128

  Fly   134 THLDNDRFYAATELFIFSRHISTGLQLDGQSALMQKLPVARKQWEILRPFHVTIKQAILTALERE 198
            :.:|.:.::.||:||||:|||||||.||.:..:|:|.|||.|||::|..|..||:.|...:|.||
Mosquito   129 SRIDREDYFVATQLFIFARHISTGLSLDTEREMMRKFPVAAKQWQVLSQFFFTIEAACRESLGRE 193

  Fly   199 ELLQEMTVDCLQSLLLLDKSDLSTVLKSFLNLRSSAFLNCLQSGPSEPRRVKDRILASLNVLNST 263
            ||...:....|.|.|||:...:...|..|...||.|||:.|....:...:|||::||||.||..|
Mosquito   194 ELSVAVVSKSLASWLLLESCPVEQTLSMFTERRSKAFLDVLDENETVYEKVKDKLLASLKVLIGT 258

  Fly   264 VELLDKCLL--------GYSLLFSR-LEECASSTCPPSINRMESSERQLVHLLPEIIAGFKPQFD 319
            |.|..:|.:        |....|.| |:........|:|..:.|.:..::.::||:||.|:|:.:
Mosquito   259 VRLFYECFVDDGTAEADGVQGGFQRELQHITGDKAAPTIGLIRSEDPMIMQMVPEMIAKFRPRLE 323

  Fly   320 VPQLTPEQLGSSLQQWLDKMNALAAAHLQQVFALVTNMQTIQDIKSAARTNGRP-DFVRLEQQLH 383
            ...|..|.:.:::..:|..:....|..|:::.:||.:::|:.|||..|....:| ::..:..:|.
Mosquito   324 RIDLAEENVRTAVSAFLRSIETTVAGRLKRLVSLVPSIKTLHDIKRQAIALDKPSNWSAVTAKLG 388

  Fly   384 LKRSQLDFYARKYVPLINARVREIIRSSWASAMKLTYEQVLLLIEAGQSQPPLQIWREQSDDLPL 448
            |... .||||..|..|||.|::.||:|:|...::.|...:|.|:..........:|:|..||:|:
Mosquito   389 LSEG-TDFYATFYQRLINDRMQSIIKSAWTETVQKTRSDLLELLAGNPGDLKAFVWKESLDDVPM 452

  Fly   449 SLAAAL---SDQPKRLANRTKGYDGATIELCKRFDSHLADIVQELNVMLQEQTTRAEDKVSLIEF 510
            :|..||   :...::|..:..||..|.:.|....:..|..:.:::...|...|....|:  ::.:
Mosquito   453 NLETALDRSNPSTRKLLMKAHGYTPALVALIGSLNGRLQTLTRDVRSFLSSSTRSEVDE--MLAY 515

  Fly   511 LRETAEEQLTEYLSNLKGLEL---RERPALLLALRNSLALVELCPNLKLCFCQPS-----SWRQW 567
            .|:...:.:.|.::..|..|.   .||.|||  .|...|:.||||.|:.||...:     ||...
Mosquito   516 FRQCCVDGVAELITATKSAEFDPTAERYALL--ARFLTAVRELCPALRECFIPTTIGLADSWHAG 578

  Fly   568 TDNSAGLGI-----EHWQRICGLIEKEMLSFWLVIVDDVLAGHNCEEKLPKV---INHEVVLSDF 624
            ..:|:.:.:     |.|.::.||:|.|.|..|.:.|:      ..:::.|.:   :.::.:|:||
Mosquito   579 RTSSSTVAMPEEDPERWAKVAGLLEDESLQCWTLWVE------RFQQRWPTLSADVGYDALLNDF 637

  Fly   625 ALWQTLTLEQRDEDQEQSVQSTIRIPSQPRLSLQTYLHQLIQALNSVVPQTLPPKVLQAFIQRLI 689
            .:|:|:|:|:.||: .|.:|||||:||||...:|..||.:.:.||..:|||:|...:...::||.
Mosquito   638 PVWETVTIEENDEN-NQPIQSTIRVPSQPSFPVQKCLHHVYELLNEAIPQTIPRPTMLDIVERLA 701

  Fly   690 GKLLCHYEGLAHAECTKASQNIALQLYFDLKFLERVFAISREERTLYDQIHAQQNQLRDYIDPFD 754
            ..||.||:.||..|..:.:|::|||.|.|::||: :..:.||::.|.::.:....:.:.||||||
Mosquito   702 TMLLKHYDVLAGTEFVQQNQSLALQYYLDVRFLQ-LLLMGREQKQLNERFNELVGRFKSYIDPFD 765

  Fly   755 FELFAEHITAHVSRAASRLQGELGVLT--PSAAAPSQGAAAASSLAHEADPNVLCLSSSGSTSLW 817
            |::|..|:.|:|.|:..:||..||.|.  ........|.:.|.:...:.:||:|.|||:....:|
Mosquito   766 FDVFYGHLNANVKRSILKLQHFLGALICHSEQLGTIVGPSGAGTEPLDKNPNILTLSSNSLNMVW 830

  Fly   818 FPLLPIVMPQAA-------GRVTSAERKSPIQEPVE-------------------------KTAT 850
            |||||:|....|       |..|::.....::|..:                         .|..
Mosquito   831 FPLLPVVCKDTASATAGSSGLTTASLGGDSLKEQQKGKSASGGGESGKSTLGSSSGNSAAGTTKQ 895

  Fly   851 TTPTRKSGGNGARKGDSSKSKSSAASFFGMSQEWFR 886
            :|....:||:....|.:......||:|||:.::|||
Mosquito   896 STKEATAGGSSTSAGTAQNYAKGAAAFFGLDKDWFR 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog1	NP_650162.1	Vps51	7..84	CDD:462568	43/76 (57%)
Cog1	XP_551520.4	None