Protein Alignment Cog1 and cog1

DIOPT Version :10

• Sequence 1: NP_650162.1
• Gene: Cog1 / 41479
• FlyBaseID: FBgn0037998
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_001342918.1
• Gene: cog1 / 2542853
• PomBaseID: SPAC144.15C
• Length: 701
• Species: Schizosaccharomyces pombe
• Alignment Length: 793
• Identity: 159/793 - (20%)
• Similarity: 287/793 - (36%)
• Gaps: 225/793 - (28%)

  Fly     9 NVDTLFEQHSVSEIDEVHKKIQSVVENKREELRTHVGERYRDLLQAADTIAAMQTSAGTLMEQVR 73
            |...:|..||:::..::.|.:...:|.|..||:.:|...|:..::|::.::.::.:    :|:|.
pombe    13 NWKEIFRTHSIAQTIQLEKFVSQQIEEKGRELQQNVCFNYQSFIEASENLSNIRNN----LEKVL 73

  Fly    74 HVQANCRSLNEQQLLGFQSTANASAKDAALK--------ERNAGKK---LQTYYGTMAQIKLLTA 127
                       |....|||..:....|...|        .:.:|..   ||.:|.     ..:..
pombe    74 -----------QNSYEFQSMVSLPKVDRVSKFLSDNESISQTSGDYFIFLQRFYA-----HAILF 122

  Fly   128 LPELIWTHLDNDRFYAATELFIFS-RHISTGLQLDGQSALMQKLPVARKQWEILRPFHVTIKQAI 191
            :.||    .:.:::..:::|.||. |.:...|..|.|..::.....:.|.:     .:..:|||:
pombe   123 VMEL----FNKEQYLQSSKLLIFCLRILPADLPNDHQCHILVNRLESCKNY-----LNNRLKQAM 178

  Fly   192 LTALEREELLQEMTVDCLQSLLLLDKSDLSTVLKSFL-----------NLR--SSAFLNCLQSGP 243
            .::|.:        |..:.|.:||:::::|:.|..||           :.|  |..|||.|:...
pombe   179 TSSLSK--------VSVVTSWILLNQANISSGLDIFLQECEDQLLILNDAREFSLTFLNTLKLAR 235

  Fly   244 SEPRRVKDRILASLN--------VLNSTVELLDKCLLGYSLLFSRLEECASSTCPPSINRMESSE 300
            ..|..::..:.||.|        :|.:.  .||:|.|  ...||  .|....|.|     .|:.:
pombe   236 DFPNEIRSYLEASKNFNIFKEKEILRNI--CLDECYL--KAYFS--AEDVKVTTP-----FETLQ 289

  Fly   301 RQLVHLLPEIIAGFKPQFDVPQLTPEQLGSSLQQWLDKMNALA-AAHLQQ-VFALVTNMQTIQDI 363
                            |||...:        ||||  |::..: .:|.:: .|:..|::.|:..|
pombe   290 ----------------QFDGDNI--------LQQW--KLSFFSKISHSEKSFFSNATSLTTLYQI 328

  Fly   364 KSAARTN-GRPDFVRLEQ------QLHL---KRSQLD---FYARKY---------VPLINARVRE 406
            .....:. ..|.|....:      |.|.   .|:.:|   .|..|.         :|..|:
pombe   329 LEGLLSELSEPQFKEFYELWNSILQNHFIISSRNIIDSLGLYVNKIKEKLQICFEIPPTNS---- 389

  Fly   407 IIRSSWASAMKLTYEQVL------LLIEAGQSQPPLQIWRE-QSDDL-------------PLSLA 451
              ...|:..:|   :|||      :|...|......:.|:. .|.|:             .|.|:
pombe   390 --FDPWSFQLK---QQVLNELKQNILPACGMDDGFQRFWQSLASFDMVLDESLQVLKKLQTLHLS 449

  Fly   452 AALSD-------QPKRLANRTKGYDGATIELCKRFDSHLADIVQELNVMLQEQTTRAEDKVSLIE 509
            ..|.|       ....|.|..|.......||...|.:::|  |.|.:...|.:|:|....|.|::
pombe   450 FTLGDIIPNYLTLADYLLNFVKTSFAQIYELVCSFVNNVA--VMESSSEKQLRTSRCLKIVRLLK 512

  Fly   510 FLRETAEE-QLTEYLSNLKGLELRERPALLLALRNSLALVELCPNLKLCFCQPSSWRQWTDNSAG 573
            ..|...|. ...:.:..|:.:.:||    |......:.:.|...||.:..|       .|.|..|
pombe   513 QFRHMDESVPFDDLIYKLQNILVRE----LTDFTTGIYINESKINLDVAAC-------ITGNFFG 566

  Fly   574 LGIEHWQRICGLIEK-EMLSFWLVIVDDVLAG------------HNCEE-KLPKVINH------- 617
            .....:..:..||:| |:|.|  .||.|...|            .|.|. |..|.::|
pombe   567 PSFALYNSLIMLIDKLEVLGF--DIVSDKFKGLLTPNLFESLFILNLERLKAAKSMDHMKQNTFD 629

  Fly   618 -EVV--LSDFA-----------LWQTLTLEQRDEDQEQSVQSTIRIPSQPRLSLQTYLHQLIQAL 668
             |.:  ||||.           ..:.:.|..:||..::...:.       |.:::..:.:|:...
pombe   630 MEFINYLSDFTNNPREVIDYQHFIELIDLHVQDEFSKEDFDTV-------RANVKECVPKLLSFF 687

  Fly   669 NSVVPQTLPPKVL 681
            ..::|:....||:
pombe   688 TVLLPRVKAQKVI 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog1	NP_650162.1	Vps51	7..84	CDD:462568	14/74 (19%)
cog1	NP_001342918.1	Vps51	7..86	CDD:462568	18/87 (21%)