Protein Alignment Cog1 and cog1

DIOPT Version :10

• Sequence 1: NP_650162.1
• Gene: Cog1 / 41479
• FlyBaseID: FBgn0037998
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_012822978.2
• Gene: cog1 / 100497164
• XenbaseID: XB-GENE-1012192
• Length: 978
• Species: Xenopus tropicalis
• Alignment Length: 1036
• Identity: 253/1036 - (24%)
• Similarity: 424/1036 - (40%)
• Gaps: 243/1036 - (23%)

  Fly    13 LFEQHSVSEIDEVHKKIQSVVENKREELRTHVGERYRDLLQAADTIAAMQTSAGTLMEQVRHVQA 77
            |||.||..||..:.:::::.:|.|:||||..||||||||::|||||..|:.|:|.::..||.::.
 Frog    16 LFEAHSAEEIRVLERRVRAEIEQKKEELRQMVGERYRDLIEAADTIGEMRRSSGLVVGAVRDMEK 80

  Fly    78 NCRSLNEQQLLGFQSTANASAKDAALKERNAGKKLQTYYGTMAQIKLLTALPELIWTHLDNDRFY 142
            .|.||..:|..|...|.         ::|.|.:..:.:|.|.||||||..:||.||:.::..::.
 Frog    81 YCGSLKCKQSTGAAGTQ---------RDRAASQCQEKFYCTAAQIKLLLEVPEKIWSAMEASQYL 136

  Fly   143 AATELFIFSRHISTGLQLDGQ----SALMQKLPVARKQWEILRPFHVTIKQAILTALEREELLQE 203
            .||:|::...|:.:.|.||..    |.::.:.|:..:|......|..||.|...:.|:......:
 Frog   137 HATQLYLLCCHLHSLLHLDSSPSRYSPVLARFPILVRQVAAAGTFRTTILQESKSLLKCPSASDQ 201

  Fly   204 MTVDCLQSLLLLDKSDLSTVLKSFLNLRSSAFLNCLQSGPSEPRRVKDRILASLNVLNSTVELLD 268
            .....|.|::||:.|.....|..:| |...|.:..|.:.|.....:|.::.       |.||||.
 Frog   202 AVAGALCSIILLEGSTPRQALTDYL-LARKAGIQQLLNQPHHGLGIKAQVC-------SLVELLA 258

  Fly   269 KCLL-GYSLLFSRLEEC---ASSTC------------------------------------PPSI 293
            ..|. .::|.:::.||.   .|.||                                    |||:
 Frog   259 NTLYQAHALFYTQSEEMKPDPSLTCGLLFTMLDTVTGQQGGGKGINVLKEEMKSVSWFKHLPPSV 323

  Fly   294 NRMESSERQLVHLLPEIIAGFKPQFDVPQLTPEQLGSSLQQWLDKMNALAAAHLQQVFALVTNMQ 358
            ...:...|.|.|                .::.|.|..:||||:...|......:..:...|.:::
 Frog   324 VNFQPERRTLAH----------------PISQEYLCETLQQWISMCNEDIKVGISALLVYVKSLK 372

  Fly   359 TIQDIKSAA------------------RTNGRP-----DFVRLEQQLHLKRSQ------LDFYAR 394
            .:..|:.|.                  |...||     |.:   |||.|:|.|      .:..:|
 Frog   373 GLAGIRDAVWELLTSESMSQNWDKVCHRLLDRPFRFWEDIL---QQLFLERLQALTKEGFESISR 434

  Fly   395 KYVPLINARVREIIRSSWASAMKLTYEQVLLLIEAGQSQPPLQIWREQSDDLPLSLAAALSDQPK 459
            ..|.|:.:.::| :..:..:...|.:|..:...          :|.|...|||.. ||.::...:
 Frog   435 NLVQLLMSSLQE-LEGNPETLKHLQHESNICSF----------LWSEGPSDLPPD-AAWVNVGSR 487

  Fly   460 RLANRTKGYDGATIE----------LCKRFDSHLADIVQELNVMLQEQ-----------TTRAED 503
            .|..|:    |.:::          ||...||.|...:::|...|..:           ||.|
 Frog   488 GLQCRS----GLSLKAQAVTPCIQSLCATLDSQLKVKLEDLCSYLPGESPVTEKHNEFVTTAA-- 546

  Fly   504 KVSLIEFLRE--TAEEQLTEY---------------LSNLK-------GLEL--RERPALLLALR 542
            |:|..:...:  |.:|.|:.:               |.::|       |:.|  .:..|:|...|
 Frog   547 KISAFDRYGDASTVQEMLSHHCLSCMQQIQDSVNTTLQSVKHEGLVDHGVALFSPKLTAVLFLAR 611

  Fly   543 NSLALVELCPNLKLC-----------FCQPSSWRQWTDNSAGLGIE------HWQRICGLIEKEM 590
            ...:|.||||:||.|           |.:|.|.::   ...|..::      .||.:...::|:.
 Frog   612 LCQSLCELCPHLKQCILGKSVSTEQSFREPRSTKK---TGKGKKVDSHAVSCKWQDLKDKLKKQS 673

  Fly   591 L---SFWLVIVDDVLAGHNCEEKLPKVINHEVV-------LSDFALWQTLTLEQRDEDQEQSVQS 645
            |   |.|...|         .:.|.....|.::       |:....|..:.: |.:.:...||.|
 Frog   674 LEAYSIWSSFV---------VKHLVTSFTHTLLINTAGSALATATHWDEIEI-QEETEAGSSVTS 728

  Fly   646 TIRIPSQPRLSLQTYLHQLIQALNSVVPQTLPPKVLQAFIQRLIGKLLCHYEGLAH--------A 702
            .||:|.|....:|..|..|.||:|:|....||...||..::..:.:::..||.|.|        .
 Frog   729 KIRLPGQCSWYVQMLLFSLCQAVNNVGGHALPRVTLQELLRHCLEEVVGAYESLCHKSLDKMKSK 793

  Fly   703 ECTKASQNIALQLYFDLKFLERVFAISREE------RTLYDQIHAQQNQLRDYIDPFDFELFAEH 761
            :.:..:|..||||.|||:::..:.: ||.|      .....:|....:||...|||||.::|..|
 Frog   794 QASSLTQARALQLLFDLRYMNLILS-SRSEDLKSSKSKQESRIQKVADQLETCIDPFDLDVFTPH 857

  Fly   762 ITAHVSRAASRLQGELGVLTPSAAAPSQGAAAASSLAHEADPNVLCLSSSGSTSLWFPLLPIVMP 826
            :.|:::|.|.|.....|:||   .|.:|....:|::..:...|||.|:||   .:.|.|||:.|.
 Frog   858 LNANLNRYAQRTSVLFGLLT---GAENQFITRSSTVGLQETHNVLPLASS---QIRFGLLPLSMS 916

  Fly   827 QAAGRVTSAERKSPIQEPVEKTATTTPTRKSG---GNGARKGDSSKSKSSAASFFGMSQEW 884
            .:......||..:.||..:.:   ..|:.:.|   |:..|:..:...::.:.|.|.:.  |
 Frog   917 SSRKTKGRAEEDAKIQVTLSE---VPPSEEEGFRPGSLFRQLATQDEEAPSQSLFKLG--W 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog1	NP_650162.1	Vps51	7..84	CDD:462568	34/70 (49%)
cog1	XP_012822978.2	Vps51	12..>67	CDD:462568	27/50 (54%)