Protein Alignment Cog1 and cog1

DIOPT Version :10

• Sequence 1: NP_650162.1
• Gene: Cog1 / 41479
• FlyBaseID: FBgn0037998
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_073800852.1
• Gene: cog1 / 100334475
• ZFINID: ZDB-GENE-050302-128
• Length: 978
• Species: Danio rerio
• Alignment Length: 1000
• Identity: 243/1000 - (24%)
• Similarity: 414/1000 - (41%)
• Gaps: 175/1000 - (17%)

  Fly    13 LFEQHSVSEIDEVHKKIQSVVENKREELRTHVGERYRDLLQAADTIAAMQTSAGTLMEQVRHVQA 77
            |||::...||..|.:|::..:|.|:||||..||||||||:.|||||..|:..:.:::..::.:..
Zfish    20 LFERYGTDEIRAVERKVRGEIEQKKEELRQMVGERYRDLIDAADTIGEMRQCSESVVHSIQDMYR 84

  Fly    78 NCRSLNEQQLLGFQSTANASAKDAALKERNAGKKLQTYYGTMAQIKLLTALPELIWTHLDNDRFY 142
            .|..|.:         |..:.:.::..|:...:..:.:|...:|||||..:||.:|:.:::.::.
Zfish    85 YCHKLKQ---------AKQTPQSSSRAEQGQKQSQEKFYTMASQIKLLLEIPERVWSAMESSQYL 140

  Fly   143 AATELFIFSRHISTGLQLDG----QSALMQKLPVARKQWEILRPFHVTIKQAILTALEREELLQE 203
            .||:|::...|:.:.|||:|    .|.::.:.|:..:|......|..||.....:.|....:..:
Zfish   141 QATQLYLLCCHLHSQLQLEGGGHQYSPVLSRFPILVRQVAAAGHFRSTILLESKSVLRGRAVSDQ 205

  Fly   204 MTVDCLQSLLLLDKSDLSTVLKSFLNLRSSAFLNCLQSGPSEPRRVKDRILASLNVLNSTVELLD 268
            ...:.|.|.:||:.|.....|..|| |...|.:..|.:.|.....||.::.       |.||||.
Zfish   206 AIAEALVSTMLLEDSSPRQALADFL-LARKASIQQLLNQPQHGAGVKAQVC-------SLVELLV 262

  Fly   269 KCL-------------------LGYSLLFSRLEECASSTCPPS----INRMESSERQLVHLLPEI 310
            ..|                   ||..|||:.||...|:|....    :::..|:.....||.|.:
Zfish   263 TTLYQAYAVFYVPPEGQVSDTGLGCGLLFTTLENVTSNTSSGKEKKVLDKEMSTGSWFKHLPPSV 327

  Fly   311 IAGFKPQFD--VPQLTPEQLGSSLQQWLDKMNALAAAHLQQVFALVTNMQTIQDIKSAARTNGRP 373
            : .|:|...  ...:..|||..:||||:|.......:.:..:...|.:::.:..|:.|.......
Zfish   328 M-NFQPVLRTLAQPIQREQLRDTLQQWIDTCKEDIRSGVSSLLVYVKSLKGLAAIRDAVWELLSS 391

  Fly   374 DFVR--------------------LEQQLHLKRSQLDFYARKYVPLINARVREIIRSSWASAMKL 418
            :.:.                    |.|||.|:|.|:  ..::....|::..|:::    :||::.
Zfish   392 ESISQHWSTVCQSLLEQPLALWDDLLQQLFLRRLQV--ITQEGTEGISSSSRQLL----SSALRD 450

  Fly   419 TYEQVLLLIEAG--------QSQPPLQIWREQSDDLP-----LSLAAALSDQPKRLANRTKGYDG 470
            ...|.    .||        :|.....:|.|...||.     :|:|.....|...|:.:|:....
Zfish   451 LQGQA----SAGSFSRGAQYESDVGAFLWSESQSDLLSDTAWVSVAQRSPQQKSGLSMKTQALTP 511

  Fly   471 ATIELCKRFDSHLADIVQELNVMLQEQTTRAE-----------------DKVSLIEFLRETAEEQ 518
            .....|...||.|...:::|...|...|...|                 |..::.:.||:.....
Zfish   512 CVQTFCSSLDSKLKAKLEDLQHYLPSDTNGKETLEKYTVSSSTPINRFMDAEAVEDILRDHCLAC 576

  Fly   519 LTEYLSNLKGLELRERPA----------LLLALRNSLALVELCPNLKLCFCQPSSW-----RQWT 568
            :.:.|::::. ||....|          :|...|...::.||||:||.|.......     |...
Zfish   577 VRDVLASVRS-ELANAQAETSSHSQLSSVLFMARLCQSMGELCPSLKQCILGKQGGVDVVSRGTP 640

  Fly   569 DNSAGLG---------IEHWQRICGLIEKEMLS-------FWLVIVDDVLAGH-----NCEEKLP 612
            ..|..||         :...|.....:::|:||       .|...:...|.|.     :.|
Zfish   641 RQSKKLGKSGTAKAADVSPAQAKWSCLKEELLSCSMDAYGIWSSALTRALVGSFAATLHAE---- 701

  Fly   613 KVINHEVVLSDFALWQTLTLEQRDEDQEQSVQSTIRIPSQPRLSLQTYLHQLIQALNSVVPQTLP 677
               |...:|.....|:.|.: |.:.:...||.|.||:|.||...:|:.|..|...:|.|....||
Zfish   702 ---NAGSILGTATNWEELEI-QEEAESGNSVMSKIRLPVQPSWYVQSLLFHLCLEVNRVGGHALP 762

  Fly   678 PKVLQAFIQRLIGKLLCHYEGLAHAECTK-----ASQNIALQLYFDLKFLERVFAISREE----R 733
            ...|...::..:.:.:..||.|.....:|     .:||.||||.|||::|........||    |
Zfish   763 KVTLLDILKGCLDQAVSEYERLTQDSQSKDTGLPMTQNRALQLLFDLRYLTVTLGSRLEEGRSSR 827

  Fly   734 TLYDQIHAQQ--NQLRDYIDPFDFELFAEHITAHVSRAASRLQGELGVLTPSAAAPSQGAAAASS 796
            :..|. ..||  :.|..:|||||.::|..|:.::::|.:.|....||:||   ....|..:.::|
Zfish   828 SQQDP-RVQQVCDSLESHIDPFDLDVFTPHLNSNLNRLSQRTSVLLGLLT---GTEKQFTSRSNS 888

  Fly   797 LAHEADPNVLCLSSSGSTSLWFPLLPIVMPQAAGRVTSAERKSPIQEPVEKTATTTPTRKS--GG 859
            :..:...|:|.|:||   .:.|.|||..|..:. :..||...:.|..|:...::|:..:.|  .|
Zfish   889 INSQEPYNILPLASS---QIRFGLLPQSMTNSR-KTNSATHGADITRPLLAPSSTSALQDSFQPG 949

  Fly   860 NGARKGDSSKSKSSAASFFGMSQEW 884
            |..|:..:.:.:|||.|.|.:.  |
Zfish   950 NLFRQLANQEEESSAPSLFKLG--W 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog1	NP_650162.1	Vps51	7..84	CDD:462568	29/70 (41%)
cog1	XP_073800852.1	None